Abdomen & clinical endpoints

About

At the Bonferroni significance level (P < 6.69e-6, multiple testing adjustment for both directions) , MR suggested 106 significant genetic causal effects (55 abdomen to clinical endpoints and 51 clinical outcomes to abdomen).

Overview of Abdomen MR results

Abdominal MR results

id.exposure	id.outcome	exp.category	out.category	method	nsnp	b	se	pval	MR.Egger.intercept Pvalue	snps
Liver volume	Alcohol use disorder, ICD-based	Liver	V Mental and behavioural disorders (F5_)	MR Egger	10	-0.12	0.25	6.53E-01	0.34	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Alcohol use disorder, ICD-based	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (fixed effects)	10	-0.34	0.08	7.10E-06	0.34	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Alcohol use disorder, ICD-based	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (multiplicative random effects)	10	-0.34	0.12	4.86E-03	0.34	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Alcohol use disorder, ICD-based	Liver	V Mental and behavioural disorders (F5_)	Weighted mode	10	-0.14	0.13	3.13E-01	0.34	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Alcohol use disorder, ICD-based	Liver	V Mental and behavioural disorders (F5_)	Weighted median	10	-0.17	0.11	1.41E-01	0.34	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Alcohol use disorder, ICD-based	Liver	V Mental and behavioural disorders (F5_)	DIVW	10	-0.34	0.08	5.41E-06	0.34	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Alcohol use disorder, ICD-based	Liver	V Mental and behavioural disorders (F5_)	GRAPPLE	10	-0.29	0.12	2.00E-02	0.34	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Alcohol use disorder, ICD-based	Liver	V Mental and behavioural disorders (F5_)	mr_raps	10	-0.30	0.08	1.31E-04	0.34	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to alcohol	Liver	V Mental and behavioural disorders (F5_)	MR Egger	10	-0.05	0.18	7.87E-01	0.12	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to alcohol	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (fixed effects)	10	-0.33	0.07	1.36E-06	0.12	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to alcohol	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (multiplicative random effects)	10	-0.33	0.10	7.56E-04	0.12	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to alcohol	Liver	V Mental and behavioural disorders (F5_)	Weighted mode	10	-0.14	0.11	2.48E-01	0.12	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to alcohol	Liver	V Mental and behavioural disorders (F5_)	Weighted median	10	-0.15	0.10	1.24E-01	0.12	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to alcohol	Liver	V Mental and behavioural disorders (F5_)	DIVW	10	-0.33	0.07	1.19E-06	0.12	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to alcohol	Liver	V Mental and behavioural disorders (F5_)	GRAPPLE	10	-0.29	0.09	2.28E-03	0.12	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to alcohol	Liver	V Mental and behavioural disorders (F5_)	mr_raps	10	-0.31	0.07	1.62E-05	0.12	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to psychoctive substance use	Liver	V Mental and behavioural disorders (F5_)	MR Egger	10	0.02	0.17	8.98E-01	0.07	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to psychoctive substance use	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (fixed effects)	10	-0.29	0.06	4.27E-06	0.07	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to psychoctive substance use	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (multiplicative random effects)	10	-0.29	0.10	2.88E-03	0.07	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to psychoctive substance use	Liver	V Mental and behavioural disorders (F5_)	Weighted mode	10	-0.11	0.10	3.05E-01	0.07	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to psychoctive substance use	Liver	V Mental and behavioural disorders (F5_)	Weighted median	10	-0.15	0.09	8.80E-02	0.07	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to psychoctive substance use	Liver	V Mental and behavioural disorders (F5_)	DIVW	10	-0.29	0.06	3.38E-06	0.07	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to psychoctive substance use	Liver	V Mental and behavioural disorders (F5_)	GRAPPLE	10	-0.25	0.09	6.75E-03	0.07	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Mental and behavioural disorders due to psychoctive substance use	Liver	V Mental and behavioural disorders (F5_)	mr_raps	10	-0.28	0.07	2.36E-05	0.07	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertensive diseases (excluding secondary)	Liver	Cardiometabolic endpoints	MR Egger	10	0.12	0.28	6.80E-01	0.53	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertensive diseases (excluding secondary)	Liver	Cardiometabolic endpoints	Inverse variance weighted (fixed effects)	10	0.28	0.04	3.79E-11	0.53	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertensive diseases (excluding secondary)	Liver	Cardiometabolic endpoints	Inverse variance weighted (multiplicative random effects)	10	0.28	0.13	3.13E-02	0.53	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertensive diseases (excluding secondary)	Liver	Cardiometabolic endpoints	Weighted mode	10	0.13	0.07	7.80E-02	0.53	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertensive diseases (excluding secondary)	Liver	Cardiometabolic endpoints	Weighted median	10	0.16	0.06	1.45E-02	0.53	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertensive diseases (excluding secondary)	Liver	Cardiometabolic endpoints	DIVW	10	0.29	0.05	1.19E-10	0.53	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertensive diseases (excluding secondary)	Liver	Cardiometabolic endpoints	GRAPPLE	10	0.35	0.13	7.49E-03	0.53	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertensive diseases (excluding secondary)	Liver	Cardiometabolic endpoints	mr_raps	10	0.24	0.04	2.65E-08	0.53	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	10	0.16	0.25	5.41E-01	0.65	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	10	0.27	0.04	2.75E-13	0.65	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	10	0.27	0.12	2.16E-02	0.65	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	10	0.15	0.06	2.63E-02	0.65	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	10	0.16	0.06	5.78E-03	0.65	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	DIVW	10	0.27	0.04	2.01E-12	0.65	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	10	0.36	0.13	4.73E-03	0.65	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	10	0.26	0.04	4.05E-12	0.65	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	10	-0.08	0.51	8.71E-01	0.62	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	10	0.15	0.04	5.37E-05	0.62	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	10	0.15	0.23	5.32E-01	0.62	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	10	-0.28	0.10	2.35E-02	0.62	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	10	-0.08	0.09	4.01E-01	0.62	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	DIVW	10	0.15	0.04	3.55E-05	0.62	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	10	0.32	0.22	1.53E-01	0.62	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Liver volume	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	10	0.55	0.04	0.00E+00	0.62	rs1009064,rs10881959,rs1260326,rs139974673,rs193084249,rs4240624,rs58489806,rs62033400,rs79287178,rs9375447
Spleen volume	Autoimmune diseases	Spleen	Diseases marked as autimmune origin	MR Egger	33	0.86	0.17	1.53E-05	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Autoimmune diseases	Spleen	Diseases marked as autimmune origin	Inverse variance weighted (fixed effects)	33	0.15	0.02	2.64E-12	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Autoimmune diseases	Spleen	Diseases marked as autimmune origin	Inverse variance weighted (multiplicative random effects)	33	0.15	0.08	7.13E-02	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Autoimmune diseases	Spleen	Diseases marked as autimmune origin	Weighted mode	33	-0.08	0.06	2.00E-01	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Autoimmune diseases	Spleen	Diseases marked as autimmune origin	Weighted median	33	-0.02	0.04	6.18E-01	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Autoimmune diseases	Spleen	Diseases marked as autimmune origin	DIVW	33	0.15	0.02	2.71E-12	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Autoimmune diseases	Spleen	Diseases marked as autimmune origin	GRAPPLE	33	-0.03	0.04	4.47E-01	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Autoimmune diseases	Spleen	Diseases marked as autimmune origin	mr_raps	33	-0.03	0.02	1.59E-01	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertensive diseases (excluding secondary)	Spleen	Cardiometabolic endpoints	MR Egger	33	0.51	0.15	1.71E-03	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertensive diseases (excluding secondary)	Spleen	Cardiometabolic endpoints	Inverse variance weighted (fixed effects)	33	0.14	0.03	3.85E-07	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertensive diseases (excluding secondary)	Spleen	Cardiometabolic endpoints	Inverse variance weighted (multiplicative random effects)	33	0.14	0.06	3.12E-02	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertensive diseases (excluding secondary)	Spleen	Cardiometabolic endpoints	Weighted mode	33	-0.12	0.12	3.43E-01	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertensive diseases (excluding secondary)	Spleen	Cardiometabolic endpoints	Weighted median	33	0.09	0.05	9.58E-02	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertensive diseases (excluding secondary)	Spleen	Cardiometabolic endpoints	DIVW	33	0.14	0.03	2.36E-07	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertensive diseases (excluding secondary)	Spleen	Cardiometabolic endpoints	GRAPPLE	33	-0.02	0.05	6.67E-01	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertensive diseases (excluding secondary)	Spleen	Cardiometabolic endpoints	mr_raps	33	0.02	0.03	3.91E-01	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Angina pectoris	Spleen	IX Diseases of the circulatory system (I9_)	MR Egger	33	0.48	0.18	1.20E-02	0.07	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Angina pectoris	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	33	0.16	0.04	7.36E-06	0.07	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Angina pectoris	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	33	0.16	0.07	2.33E-02	0.07	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Angina pectoris	Spleen	IX Diseases of the circulatory system (I9_)	Weighted mode	33	-0.09	0.11	4.51E-01	0.07	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Angina pectoris	Spleen	IX Diseases of the circulatory system (I9_)	Weighted median	33	0.06	0.07	3.92E-01	0.07	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Angina pectoris	Spleen	IX Diseases of the circulatory system (I9_)	DIVW	33	0.17	0.04	4.18E-06	0.07	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Angina pectoris	Spleen	IX Diseases of the circulatory system (I9_)	GRAPPLE	33	0.05	0.07	5.15E-01	0.07	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Angina pectoris	Spleen	IX Diseases of the circulatory system (I9_)	mr_raps	33	0.04	0.04	2.46E-01	0.07	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary angiopasty	Spleen	IX Diseases of the circulatory system (I9_)	MR Egger	33	0.61	0.24	1.54E-02	0.12	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary angiopasty	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	33	0.26	0.05	4.94E-07	0.12	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary angiopasty	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	33	0.26	0.09	6.46E-03	0.12	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary angiopasty	Spleen	IX Diseases of the circulatory system (I9_)	Weighted mode	33	0.49	0.15	2.84E-03	0.12	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary angiopasty	Spleen	IX Diseases of the circulatory system (I9_)	Weighted median	33	0.19	0.10	4.37E-02	0.12	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary angiopasty	Spleen	IX Diseases of the circulatory system (I9_)	DIVW	33	0.26	0.05	3.01E-07	0.12	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary angiopasty	Spleen	IX Diseases of the circulatory system (I9_)	GRAPPLE	33	0.16	0.10	8.76E-02	0.12	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary angiopasty	Spleen	IX Diseases of the circulatory system (I9_)	mr_raps	33	0.14	0.05	5.51E-03	0.12	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Atherosclerosis, excluding cerebral, coronary and PAD	Spleen	IX Diseases of the circulatory system (I9_)	MR Egger	33	0.62	0.15	2.05E-04	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Atherosclerosis, excluding cerebral, coronary and PAD	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	33	0.24	0.05	1.13E-06	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Atherosclerosis, excluding cerebral, coronary and PAD	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	33	0.24	0.06	1.06E-04	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Atherosclerosis, excluding cerebral, coronary and PAD	Spleen	IX Diseases of the circulatory system (I9_)	Weighted mode	33	0.49	0.09	4.79E-06	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Atherosclerosis, excluding cerebral, coronary and PAD	Spleen	IX Diseases of the circulatory system (I9_)	Weighted median	33	0.35	0.08	8.64E-06	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Atherosclerosis, excluding cerebral, coronary and PAD	Spleen	IX Diseases of the circulatory system (I9_)	DIVW	33	0.25	0.05	6.74E-07	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Atherosclerosis, excluding cerebral, coronary and PAD	Spleen	IX Diseases of the circulatory system (I9_)	GRAPPLE	33	0.24	0.06	2.26E-04	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Atherosclerosis, excluding cerebral, coronary and PAD	Spleen	IX Diseases of the circulatory system (I9_)	mr_raps	33	0.24	0.05	5.49E-06	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Major coronary heart disease event	Spleen	IX Diseases of the circulatory system (I9_)	MR Egger	33	0.62	0.17	1.01E-03	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Major coronary heart disease event	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	33	0.19	0.03	7.24E-09	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Major coronary heart disease event	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	33	0.19	0.07	9.51E-03	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Major coronary heart disease event	Spleen	IX Diseases of the circulatory system (I9_)	Weighted mode	33	0.02	0.17	8.99E-01	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Major coronary heart disease event	Spleen	IX Diseases of the circulatory system (I9_)	Weighted median	33	0.09	0.06	1.48E-01	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Major coronary heart disease event	Spleen	IX Diseases of the circulatory system (I9_)	DIVW	33	0.19	0.03	5.10E-09	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Major coronary heart disease event	Spleen	IX Diseases of the circulatory system (I9_)	GRAPPLE	33	0.10	0.07	1.59E-01	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Major coronary heart disease event	Spleen	IX Diseases of the circulatory system (I9_)	mr_raps	33	0.07	0.03	2.57E-02	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary atherosclerosis	Spleen	IX Diseases of the circulatory system (I9_)	MR Egger	33	0.64	0.17	6.81E-04	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary atherosclerosis	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	33	0.20	0.03	6.95E-10	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary atherosclerosis	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	33	0.20	0.07	5.67E-03	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary atherosclerosis	Spleen	IX Diseases of the circulatory system (I9_)	Weighted mode	33	0.36	0.19	6.96E-02	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary atherosclerosis	Spleen	IX Diseases of the circulatory system (I9_)	Weighted median	33	0.16	0.07	1.43E-02	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary atherosclerosis	Spleen	IX Diseases of the circulatory system (I9_)	DIVW	33	0.20	0.03	5.39E-10	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary atherosclerosis	Spleen	IX Diseases of the circulatory system (I9_)	GRAPPLE	33	0.10	0.07	1.34E-01	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Coronary atherosclerosis	Spleen	IX Diseases of the circulatory system (I9_)	mr_raps	33	0.08	0.03	1.95E-02	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hard cardiovascular diseases	Spleen	Cardiometabolic endpoints	MR Egger	33	0.52	0.13	5.01E-04	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hard cardiovascular diseases	Spleen	Cardiometabolic endpoints	Inverse variance weighted (fixed effects)	33	0.14	0.03	7.24E-07	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hard cardiovascular diseases	Spleen	Cardiometabolic endpoints	Inverse variance weighted (multiplicative random effects)	33	0.14	0.06	1.35E-02	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hard cardiovascular diseases	Spleen	Cardiometabolic endpoints	Weighted mode	33	-0.08	0.13	5.49E-01	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hard cardiovascular diseases	Spleen	Cardiometabolic endpoints	Weighted median	33	0.05	0.05	3.20E-01	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hard cardiovascular diseases	Spleen	Cardiometabolic endpoints	DIVW	33	0.14	0.03	4.37E-07	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hard cardiovascular diseases	Spleen	Cardiometabolic endpoints	GRAPPLE	33	0.03	0.05	6.28E-01	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hard cardiovascular diseases	Spleen	Cardiometabolic endpoints	mr_raps	33	0.02	0.03	5.41E-01	0.00	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Diseases of arteries, arterioles and capillaries	Spleen	IX Diseases of the circulatory system (I9_)	MR Egger	33	0.44	0.12	8.96E-04	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Diseases of arteries, arterioles and capillaries	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	33	0.16	0.04	2.69E-05	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Diseases of arteries, arterioles and capillaries	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	33	0.16	0.05	1.60E-03	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Diseases of arteries, arterioles and capillaries	Spleen	IX Diseases of the circulatory system (I9_)	Weighted mode	33	0.34	0.07	1.88E-05	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Diseases of arteries, arterioles and capillaries	Spleen	IX Diseases of the circulatory system (I9_)	Weighted median	33	0.33	0.06	1.21E-08	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Diseases of arteries, arterioles and capillaries	Spleen	IX Diseases of the circulatory system (I9_)	DIVW	33	0.16	0.04	1.48E-05	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Diseases of arteries, arterioles and capillaries	Spleen	IX Diseases of the circulatory system (I9_)	GRAPPLE	33	0.18	0.05	8.28E-04	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Diseases of arteries, arterioles and capillaries	Spleen	IX Diseases of the circulatory system (I9_)	mr_raps	33	0.18	0.04	3.62E-06	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Heart failure and antihypertensive medication	Spleen	Cardiometabolic endpoints	MR Egger	33	0.53	0.20	1.03E-02	0.08	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Heart failure and antihypertensive medication	Spleen	Cardiometabolic endpoints	Inverse variance weighted (fixed effects)	33	0.21	0.05	1.65E-05	0.08	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Heart failure and antihypertensive medication	Spleen	Cardiometabolic endpoints	Inverse variance weighted (multiplicative random effects)	33	0.21	0.08	7.03E-03	0.08	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Heart failure and antihypertensive medication	Spleen	Cardiometabolic endpoints	Weighted mode	33	0.51	0.12	1.89E-04	0.08	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Heart failure and antihypertensive medication	Spleen	Cardiometabolic endpoints	Weighted median	33	0.16	0.09	7.77E-02	0.08	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Heart failure and antihypertensive medication	Spleen	Cardiometabolic endpoints	DIVW	33	0.21	0.05	9.18E-06	0.08	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Heart failure and antihypertensive medication	Spleen	Cardiometabolic endpoints	GRAPPLE	33	0.14	0.08	6.81E-02	0.08	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Heart failure and antihypertensive medication	Spleen	Cardiometabolic endpoints	mr_raps	33	0.14	0.05	4.03E-03	0.08	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertension	Spleen	IX Diseases of the circulatory system (I9_)	MR Egger	33	0.40	0.14	6.61E-03	0.04	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertension	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	33	0.12	0.02	8.08E-08	0.04	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertension	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	33	0.12	0.06	3.02E-02	0.04	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertension	Spleen	IX Diseases of the circulatory system (I9_)	Weighted mode	33	-0.08	0.09	3.75E-01	0.04	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertension	Spleen	IX Diseases of the circulatory system (I9_)	Weighted median	33	0.05	0.05	2.46E-01	0.04	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertension	Spleen	IX Diseases of the circulatory system (I9_)	DIVW	33	0.13	0.02	5.21E-08	0.04	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertension	Spleen	IX Diseases of the circulatory system (I9_)	GRAPPLE	33	-0.01	0.05	8.25E-01	0.04	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Hypertension	Spleen	IX Diseases of the circulatory system (I9_)	mr_raps	33	0.03	0.02	2.59E-01	0.04	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Ischemic heart diseases	Spleen	IX Diseases of the circulatory system (I9_)	MR Egger	33	0.47	0.14	1.87E-03	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Ischemic heart diseases	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	33	0.15	0.03	2.50E-07	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Ischemic heart diseases	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	33	0.15	0.06	1.18E-02	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Ischemic heart diseases	Spleen	IX Diseases of the circulatory system (I9_)	Weighted mode	33	0.31	0.10	4.21E-03	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Ischemic heart diseases	Spleen	IX Diseases of the circulatory system (I9_)	Weighted median	33	0.13	0.06	2.33E-02	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Ischemic heart diseases	Spleen	IX Diseases of the circulatory system (I9_)	DIVW	33	0.15	0.03	1.56E-07	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Ischemic heart diseases	Spleen	IX Diseases of the circulatory system (I9_)	GRAPPLE	33	0.06	0.06	2.50E-01	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Ischemic heart diseases	Spleen	IX Diseases of the circulatory system (I9_)	mr_raps	33	0.06	0.03	4.90E-02	0.02	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Peripheral artery disease	Spleen	IX Diseases of the circulatory system (I9_)	MR Egger	33	0.60	0.14	1.39E-04	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Peripheral artery disease	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	33	0.23	0.05	1.63E-06	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Peripheral artery disease	Spleen	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	33	0.23	0.06	7.24E-05	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Peripheral artery disease	Spleen	IX Diseases of the circulatory system (I9_)	Weighted mode	33	0.48	0.09	9.15E-06	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Peripheral artery disease	Spleen	IX Diseases of the circulatory system (I9_)	Weighted median	33	0.32	0.08	4.98E-05	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Peripheral artery disease	Spleen	IX Diseases of the circulatory system (I9_)	DIVW	33	0.24	0.05	9.63E-07	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Peripheral artery disease	Spleen	IX Diseases of the circulatory system (I9_)	GRAPPLE	33	0.22	0.06	3.26E-04	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Spleen volume	Peripheral artery disease	Spleen	IX Diseases of the circulatory system (I9_)	mr_raps	33	0.22	0.05	1.90E-05	0.01	rs10894986,rs111907377,rs1150779,rs11658587,rs11676298,rs118083884,rs12034941,rs12206651,rs12376511,rs12491937,rs12899025,rs169738,rs17011755,rs1861270,rs34753522,rs3731211,rs374039502,rs4429673,rs4444903,rs4455005,rs4768862,rs4896089,rs55968914,rs56043070,rs61750929,rs61963226,rs641154,rs66800452,rs7137828,rs7734992,rs785455,rs857721,rs9376091
Kidney volume	Stroke, including SAH	Kidney	IX Diseases of the circulatory system (I9_)	MR Egger	10	0.11	0.48	8.23E-01	0.77	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Stroke, including SAH	Kidney	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	10	0.25	0.09	2.92E-03	0.77	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Stroke, including SAH	Kidney	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	10	0.25	0.06	3.33E-05	0.77	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Stroke, including SAH	Kidney	IX Diseases of the circulatory system (I9_)	Weighted mode	10	0.38	0.18	6.15E-02	0.77	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Stroke, including SAH	Kidney	IX Diseases of the circulatory system (I9_)	Weighted median	10	0.30	0.11	8.17E-03	0.77	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Stroke, including SAH	Kidney	IX Diseases of the circulatory system (I9_)	DIVW	10	0.26	0.09	1.64E-03	0.77	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Stroke, including SAH	Kidney	IX Diseases of the circulatory system (I9_)	GRAPPLE	10	0.26	0.09	3.90E-03	0.77	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Stroke, including SAH	Kidney	IX Diseases of the circulatory system (I9_)	mr_raps	10	0.26	0.09	4.99E-03	0.77	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Chronic kidney disease	Kidney	XIV Diseases of the genitourinary system (N14_)	MR Egger	10	-4.47	2.72	1.39E-01	0.18	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Chronic kidney disease	Kidney	XIV Diseases of the genitourinary system (N14_)	Inverse variance weighted (fixed effects)	10	-0.58	0.14	4.38E-05	0.18	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Chronic kidney disease	Kidney	XIV Diseases of the genitourinary system (N14_)	Inverse variance weighted (multiplicative random effects)	10	-0.58	0.52	2.65E-01	0.18	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Chronic kidney disease	Kidney	XIV Diseases of the genitourinary system (N14_)	Weighted mode	10	-0.33	0.25	2.26E-01	0.18	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Chronic kidney disease	Kidney	XIV Diseases of the genitourinary system (N14_)	Weighted median	10	-0.26	0.20	2.09E-01	0.18	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Chronic kidney disease	Kidney	XIV Diseases of the genitourinary system (N14_)	DIVW	10	-0.59	0.15	3.22E-05	0.18	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Chronic kidney disease	Kidney	XIV Diseases of the genitourinary system (N14_)	GRAPPLE	10	-0.21	0.45	6.44E-01	0.18	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Chronic kidney disease	Kidney	XIV Diseases of the genitourinary system (N14_)	mr_raps	10	-0.21	0.13	1.03E-01	0.18	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Renal failure	Kidney	XIV Diseases of the genitourinary system (N14_)	MR Egger	10	-3.18	1.72	1.01E-01	0.16	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Renal failure	Kidney	XIV Diseases of the genitourinary system (N14_)	Inverse variance weighted (fixed effects)	10	-0.55	0.12	1.91E-06	0.16	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Renal failure	Kidney	XIV Diseases of the genitourinary system (N14_)	Inverse variance weighted (multiplicative random effects)	10	-0.55	0.33	9.78E-02	0.16	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Renal failure	Kidney	XIV Diseases of the genitourinary system (N14_)	Weighted mode	10	-0.41	0.21	8.27E-02	0.16	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Renal failure	Kidney	XIV Diseases of the genitourinary system (N14_)	Weighted median	10	-0.36	0.18	3.93E-02	0.16	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Renal failure	Kidney	XIV Diseases of the genitourinary system (N14_)	DIVW	10	-0.56	0.12	1.90E-06	0.16	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Renal failure	Kidney	XIV Diseases of the genitourinary system (N14_)	GRAPPLE	10	-0.39	0.31	2.00E-01	0.16	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Kidney volume	Renal failure	Kidney	XIV Diseases of the genitourinary system (N14_)	mr_raps	10	-0.37	0.11	1.04E-03	0.16	rs1032296,rs10810526,rs2282040,rs56005989,rs7193144,rs744103,rs77924615,rs807624,rs863678,rs9895661
Visceral adipose tissue measurement	Sleep apnoea, including avohilmo	Adipose tissue	VI Diseases of the nervous system (G6_)	MR Egger	6	-4.96	1.90	5.94E-02	0.05	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Sleep apnoea, including avohilmo	Adipose tissue	VI Diseases of the nervous system (G6_)	Inverse variance weighted (fixed effects)	6	0.39	0.09	1.67E-05	0.05	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Sleep apnoea, including avohilmo	Adipose tissue	VI Diseases of the nervous system (G6_)	Inverse variance weighted (multiplicative random effects)	6	0.39	0.40	3.27E-01	0.05	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Sleep apnoea, including avohilmo	Adipose tissue	VI Diseases of the nervous system (G6_)	Weighted mode	6	-0.09	0.12	4.86E-01	0.05	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Sleep apnoea, including avohilmo	Adipose tissue	VI Diseases of the nervous system (G6_)	Weighted median	6	0.01	0.13	9.47E-01	0.05	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Sleep apnoea, including avohilmo	Adipose tissue	VI Diseases of the nervous system (G6_)	DIVW	6	0.40	0.10	1.90E-05	0.05	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Sleep apnoea, including avohilmo	Adipose tissue	VI Diseases of the nervous system (G6_)	GRAPPLE	6	0.20	0.39	6.09E-01	0.05	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Sleep apnoea, including avohilmo	Adipose tissue	VI Diseases of the nervous system (G6_)	mr_raps	6	0.07	0.08	3.78E-01	0.05	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Adipose tissue	IX Diseases of the circulatory system (I9_)	MR Egger	6	-1.54	1.09	2.29E-01	0.16	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Adipose tissue	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	6	0.33	0.08	2.68E-05	0.16	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Adipose tissue	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	6	0.33	0.17	5.68E-02	0.16	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Adipose tissue	IX Diseases of the circulatory system (I9_)	Weighted mode	6	0.15	0.17	4.25E-01	0.16	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Adipose tissue	IX Diseases of the circulatory system (I9_)	Weighted median	6	0.21	0.12	9.45E-02	0.16	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Adipose tissue	IX Diseases of the circulatory system (I9_)	DIVW	6	0.34	0.09	2.83E-05	0.16	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Adipose tissue	IX Diseases of the circulatory system (I9_)	GRAPPLE	6	0.28	0.18	1.11E-01	0.16	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Adipose tissue	IX Diseases of the circulatory system (I9_)	mr_raps	6	0.32	0.08	1.18E-04	0.16	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Irregular menses	Adipose tissue	XIV Diseases of the genitourinary system (N14_)	MR Egger	6	-0.97	0.99	3.83E-01	0.57	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Irregular menses	Adipose tissue	XIV Diseases of the genitourinary system (N14_)	Inverse variance weighted (fixed effects)	6	-0.37	0.13	5.97E-03	0.57	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Irregular menses	Adipose tissue	XIV Diseases of the genitourinary system (N14_)	Inverse variance weighted (multiplicative random effects)	6	-0.37	0.08	1.45E-05	0.57	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Irregular menses	Adipose tissue	XIV Diseases of the genitourinary system (N14_)	Weighted mode	6	-0.47	0.23	1.03E-01	0.57	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Irregular menses	Adipose tissue	XIV Diseases of the genitourinary system (N14_)	Weighted median	6	-0.45	0.16	6.22E-03	0.57	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Irregular menses	Adipose tissue	XIV Diseases of the genitourinary system (N14_)	DIVW	6	-0.38	0.14	3.47E-03	0.57	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Irregular menses	Adipose tissue	XIV Diseases of the genitourinary system (N14_)	GRAPPLE	6	-0.38	0.14	7.78E-03	0.57	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Visceral adipose tissue measurement	Irregular menses	Adipose tissue	XIV Diseases of the genitourinary system (N14_)	mr_raps	6	-0.37	0.14	1.03E-02	0.57	rs11666808,rs153701,rs157845,rs62048402,rs73221948,rs8101436
Percent Liver fat	Dementia, including avohilmo	Liver	V Mental and behavioural disorders (F5_)	MR Egger	13	-0.19	0.40	6.54E-01	0.76	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia, including avohilmo	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (fixed effects)	13	-0.28	0.03	4.84E-23	0.76	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia, including avohilmo	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (multiplicative random effects)	13	-0.28	0.25	2.67E-01	0.76	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia, including avohilmo	Liver	V Mental and behavioural disorders (F5_)	Weighted mode	13	-0.02	0.03	5.63E-01	0.76	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia, including avohilmo	Liver	V Mental and behavioural disorders (F5_)	Weighted median	13	-0.01	0.04	7.10E-01	0.76	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia, including avohilmo	Liver	V Mental and behavioural disorders (F5_)	DIVW	13	-0.28	0.03	0.00E+00	0.76	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia, including avohilmo	Liver	V Mental and behavioural disorders (F5_)	GRAPPLE	13	-0.02	0.05	7.43E-01	0.76	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia, including avohilmo	Liver	V Mental and behavioural disorders (F5_)	mr_raps	13	-0.03	0.02	2.10E-01	0.76	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia	Liver	V Mental and behavioural disorders (F5_)	MR Egger	13	-0.26	0.74	7.27E-01	0.79	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (fixed effects)	13	-0.41	0.04	1.80E-20	0.79	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (multiplicative random effects)	13	-0.41	0.47	3.78E-01	0.79	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia	Liver	V Mental and behavioural disorders (F5_)	Weighted mode	13	-0.03	0.05	5.93E-01	0.79	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia	Liver	V Mental and behavioural disorders (F5_)	Weighted median	13	-0.02	0.05	7.60E-01	0.79	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia	Liver	V Mental and behavioural disorders (F5_)	DIVW	13	-0.42	0.05	0.00E+00	0.79	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia	Liver	V Mental and behavioural disorders (F5_)	GRAPPLE	13	-0.03	0.06	6.60E-01	0.79	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Dementia	Liver	V Mental and behavioural disorders (F5_)	mr_raps	13	-0.04	0.04	2.44E-01	0.79	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Psychiatric diseases	Liver	V Mental and behavioural disorders (F5_)	MR Egger	13	-0.08	0.16	6.10E-01	0.90	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Psychiatric diseases	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (fixed effects)	13	-0.10	0.02	5.51E-08	0.90	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Psychiatric diseases	Liver	V Mental and behavioural disorders (F5_)	Inverse variance weighted (multiplicative random effects)	13	-0.10	0.10	3.23E-01	0.90	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Psychiatric diseases	Liver	V Mental and behavioural disorders (F5_)	Weighted mode	13	-0.01	0.02	6.12E-01	0.90	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Psychiatric diseases	Liver	V Mental and behavioural disorders (F5_)	Weighted median	13	-0.01	0.02	7.54E-01	0.90	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Psychiatric diseases	Liver	V Mental and behavioural disorders (F5_)	DIVW	13	-0.10	0.02	3.90E-08	0.90	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Psychiatric diseases	Liver	V Mental and behavioural disorders (F5_)	GRAPPLE	13	0.00	0.04	9.19E-01	0.90	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Psychiatric diseases	Liver	V Mental and behavioural disorders (F5_)	mr_raps	13	-0.01	0.02	4.60E-01	0.90	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer‚Äôs disease, wide definition	Liver	VI Diseases of the nervous system (G6_)	MR Egger	13	-0.27	0.82	7.50E-01	0.81	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer‚Äôs disease, wide definition	Liver	VI Diseases of the nervous system (G6_)	Inverse variance weighted (fixed effects)	13	-0.42	0.05	3.39E-17	0.81	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer‚Äôs disease, wide definition	Liver	VI Diseases of the nervous system (G6_)	Inverse variance weighted (multiplicative random effects)	13	-0.42	0.52	4.25E-01	0.81	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer‚Äôs disease, wide definition	Liver	VI Diseases of the nervous system (G6_)	Weighted mode	13	0.00	0.06	9.57E-01	0.81	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer‚Äôs disease, wide definition	Liver	VI Diseases of the nervous system (G6_)	Weighted median	13	-0.01	0.07	9.03E-01	0.81	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer‚Äôs disease, wide definition	Liver	VI Diseases of the nervous system (G6_)	DIVW	13	-0.42	0.05	1.11E-16	0.81	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer‚Äôs disease, wide definition	Liver	VI Diseases of the nervous system (G6_)	GRAPPLE	13	0.01	0.06	8.50E-01	0.81	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer‚Äôs disease, wide definition	Liver	VI Diseases of the nervous system (G6_)	mr_raps	13	0.00	0.04	9.26E-01	0.81	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease, including avohilmo	Liver	VI Diseases of the nervous system (G6_)	MR Egger	13	-0.24	0.87	7.89E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease, including avohilmo	Liver	VI Diseases of the nervous system (G6_)	Inverse variance weighted (fixed effects)	13	-0.51	0.05	6.75E-22	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease, including avohilmo	Liver	VI Diseases of the nervous system (G6_)	Inverse variance weighted (multiplicative random effects)	13	-0.51	0.56	3.59E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease, including avohilmo	Liver	VI Diseases of the nervous system (G6_)	Weighted mode	13	-0.05	0.07	5.03E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease, including avohilmo	Liver	VI Diseases of the nervous system (G6_)	Weighted median	13	-0.03	0.08	6.65E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease, including avohilmo	Liver	VI Diseases of the nervous system (G6_)	DIVW	13	-0.51	0.06	0.00E+00	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease, including avohilmo	Liver	VI Diseases of the nervous system (G6_)	GRAPPLE	13	-0.05	0.08	5.32E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease, including avohilmo	Liver	VI Diseases of the nervous system (G6_)	mr_raps	13	-0.08	0.04	5.79E-02	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease	Liver	VI Diseases of the nervous system (G6_)	MR Egger	13	-0.31	0.96	7.51E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease	Liver	VI Diseases of the nervous system (G6_)	Inverse variance weighted (fixed effects)	13	-0.61	0.06	1.24E-25	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease	Liver	VI Diseases of the nervous system (G6_)	Inverse variance weighted (multiplicative random effects)	13	-0.61	0.60	3.14E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease	Liver	VI Diseases of the nervous system (G6_)	Weighted mode	13	-0.01	0.07	9.37E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease	Liver	VI Diseases of the nervous system (G6_)	Weighted median	13	0.00	0.07	9.51E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease	Liver	VI Diseases of the nervous system (G6_)	DIVW	13	-0.61	0.06	0.00E+00	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease	Liver	VI Diseases of the nervous system (G6_)	GRAPPLE	13	-0.02	0.06	6.92E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Alzheimer disease	Liver	VI Diseases of the nervous system (G6_)	mr_raps	13	-0.05	0.05	2.76E-01	0.69	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Other degenerative diseases of the nervous system	Liver	VI Diseases of the nervous system (G6_)	MR Egger	13	-0.27	0.87	7.62E-01	0.66	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Other degenerative diseases of the nervous system	Liver	VI Diseases of the nervous system (G6_)	Inverse variance weighted (fixed effects)	13	-0.57	0.05	1.03E-26	0.66	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Other degenerative diseases of the nervous system	Liver	VI Diseases of the nervous system (G6_)	Inverse variance weighted (multiplicative random effects)	13	-0.57	0.55	3.03E-01	0.66	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Other degenerative diseases of the nervous system	Liver	VI Diseases of the nervous system (G6_)	Weighted mode	13	0.02	0.07	7.44E-01	0.66	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Other degenerative diseases of the nervous system	Liver	VI Diseases of the nervous system (G6_)	Weighted median	13	0.01	0.07	8.71E-01	0.66	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Other degenerative diseases of the nervous system	Liver	VI Diseases of the nervous system (G6_)	DIVW	13	-0.57	0.06	0.00E+00	0.66	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Other degenerative diseases of the nervous system	Liver	VI Diseases of the nervous system (G6_)	GRAPPLE	13	-0.01	0.06	9.33E-01	0.66	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Other degenerative diseases of the nervous system	Liver	VI Diseases of the nervous system (G6_)	mr_raps	13	-0.03	0.04	4.70E-01	0.66	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Angina pectoris	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	13	-0.26	0.10	2.71E-02	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Angina pectoris	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	13	-0.15	0.03	1.90E-06	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Angina pectoris	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	13	-0.15	0.07	3.66E-02	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Angina pectoris	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	13	-0.16	0.04	2.94E-03	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Angina pectoris	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	13	-0.18	0.05	1.06E-03	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Angina pectoris	Liver	IX Diseases of the circulatory system (I9_)	DIVW	13	-0.15	0.03	1.17E-06	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Angina pectoris	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	13	-0.19	0.06	2.82E-03	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Angina pectoris	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	13	-0.18	0.03	2.18E-08	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Major coronary heart disease event	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	13	-0.30	0.10	1.07E-02	0.10	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Major coronary heart disease event	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	13	-0.17	0.03	1.20E-09	0.10	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Major coronary heart disease event	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	13	-0.17	0.07	1.68E-02	0.10	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Major coronary heart disease event	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	13	-0.18	0.03	2.10E-04	0.10	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Major coronary heart disease event	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	13	-0.18	0.04	7.65E-06	0.10	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Major coronary heart disease event	Liver	IX Diseases of the circulatory system (I9_)	DIVW	13	-0.17	0.03	1.03E-09	0.10	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Major coronary heart disease event	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	13	-0.20	0.06	9.40E-04	0.10	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Major coronary heart disease event	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	13	-0.17	0.03	2.84E-09	0.10	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Coronary atherosclerosis	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	13	-0.28	0.11	2.46E-02	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Coronary atherosclerosis	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	13	-0.16	0.03	9.02E-09	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Coronary atherosclerosis	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	13	-0.16	0.07	3.09E-02	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Coronary atherosclerosis	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	13	-0.18	0.04	7.46E-04	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Coronary atherosclerosis	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	13	-0.23	0.05	1.32E-06	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Coronary atherosclerosis	Liver	IX Diseases of the circulatory system (I9_)	DIVW	13	-0.16	0.03	6.96E-09	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Coronary atherosclerosis	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	13	-0.20	0.07	1.96E-03	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Coronary atherosclerosis	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	13	-0.18	0.03	1.03E-10	0.17	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hard cardiovascular diseases	Liver	Cardiometabolic endpoints	MR Egger	13	-0.21	0.08	2.59E-02	0.12	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hard cardiovascular diseases	Liver	Cardiometabolic endpoints	Inverse variance weighted (fixed effects)	13	-0.11	0.02	1.08E-05	0.12	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hard cardiovascular diseases	Liver	Cardiometabolic endpoints	Inverse variance weighted (multiplicative random effects)	13	-0.11	0.06	6.13E-02	0.12	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hard cardiovascular diseases	Liver	Cardiometabolic endpoints	Weighted mode	13	-0.11	0.03	2.49E-03	0.12	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hard cardiovascular diseases	Liver	Cardiometabolic endpoints	Weighted median	13	-0.11	0.03	1.20E-03	0.12	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hard cardiovascular diseases	Liver	Cardiometabolic endpoints	DIVW	13	-0.11	0.02	6.31E-06	0.12	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hard cardiovascular diseases	Liver	Cardiometabolic endpoints	GRAPPLE	13	-0.12	0.05	1.72E-02	0.12	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hard cardiovascular diseases	Liver	Cardiometabolic endpoints	mr_raps	13	-0.11	0.02	2.04E-05	0.12	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	13	0.06	0.06	3.31E-01	0.74	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	13	0.04	0.02	2.26E-02	0.74	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	13	0.04	0.04	2.29E-01	0.74	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	13	0.12	0.05	3.33E-02	0.74	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	13	0.09	0.03	4.95E-03	0.74	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	DIVW	13	0.04	0.02	1.14E-02	0.74	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	13	0.09	0.04	1.34E-02	0.74	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Hypertension	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	13	0.09	0.02	7.34E-06	0.74	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Ischemic heart diseases	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	13	-0.22	0.09	2.58E-02	0.20	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Ischemic heart diseases	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	13	-0.13	0.02	3.12E-08	0.20	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Ischemic heart diseases	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	13	-0.13	0.06	2.19E-02	0.20	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Ischemic heart diseases	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	13	-0.15	0.03	9.54E-04	0.20	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Ischemic heart diseases	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	13	-0.20	0.04	3.73E-07	0.20	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Ischemic heart diseases	Liver	IX Diseases of the circulatory system (I9_)	DIVW	13	-0.13	0.02	2.27E-08	0.20	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Ischemic heart diseases	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	13	-0.17	0.05	1.75E-03	0.20	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Ischemic heart diseases	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	13	-0.15	0.02	4.41E-10	0.20	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Myocardial infarction	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	13	-0.28	0.11	2.17E-02	0.24	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Myocardial infarction	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	13	-0.18	0.04	1.92E-07	0.24	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Myocardial infarction	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	13	-0.18	0.07	8.96E-03	0.24	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Myocardial infarction	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	13	-0.16	0.06	1.58E-02	0.24	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Myocardial infarction	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	13	-0.18	0.06	1.04E-03	0.24	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Myocardial infarction	Liver	IX Diseases of the circulatory system (I9_)	DIVW	13	-0.18	0.04	1.28E-07	0.24	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Myocardial infarction	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	13	-0.21	0.07	1.72E-03	0.24	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Myocardial infarction	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	13	-0.16	0.04	5.45E-06	0.24	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	13	-0.62	0.28	4.96E-02	0.15	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	13	-0.29	0.02	6.88E-53	0.15	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	13	-0.29	0.19	1.35E-01	0.15	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	13	-0.25	0.03	5.18E-07	0.15	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	13	-0.25	0.04	2.69E-12	0.15	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	DIVW	13	-0.29	0.02	0.00E+00	0.15	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	13	-0.29	0.14	4.06E-02	0.15	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Percent Liver fat	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	13	-0.30	0.02	0.00E+00	0.15	rs10787429,rs112875651,rs12562744,rs188247550,rs2642438,rs429358,rs4665985,rs55714539,rs55736117,rs58542926,rs7029757,rs738409,rs7689584
Liver iron content	Autoimmune diseases	Liver	Diseases marked as autimmune origin	MR Egger	12	0.03	0.17	8.46E-01	0.28	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Autoimmune diseases	Liver	Diseases marked as autimmune origin	Inverse variance weighted (fixed effects)	12	-0.11	0.02	2.95E-08	0.28	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Autoimmune diseases	Liver	Diseases marked as autimmune origin	Inverse variance weighted (multiplicative random effects)	12	-0.11	0.12	3.32E-01	0.28	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Autoimmune diseases	Liver	Diseases marked as autimmune origin	Weighted mode	12	-0.01	0.02	7.61E-01	0.28	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Autoimmune diseases	Liver	Diseases marked as autimmune origin	Weighted median	12	0.00	0.03	8.89E-01	0.28	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Autoimmune diseases	Liver	Diseases marked as autimmune origin	DIVW	12	-0.11	0.02	1.86E-08	0.28	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Autoimmune diseases	Liver	Diseases marked as autimmune origin	GRAPPLE	12	-0.07	0.08	4.06E-01	0.28	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Autoimmune diseases	Liver	Diseases marked as autimmune origin	mr_raps	12	-0.03	0.02	9.38E-02	0.28	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Liver	Cardiometabolic endpoints	MR Egger	12	0.14	0.08	9.79E-02	0.92	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Liver	Cardiometabolic endpoints	Inverse variance weighted (fixed effects)	12	0.14	0.03	1.62E-05	0.92	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Liver	Cardiometabolic endpoints	Inverse variance weighted (multiplicative random effects)	12	0.14	0.05	5.63E-03	0.92	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Liver	Cardiometabolic endpoints	Weighted mode	12	0.10	0.04	2.57E-02	0.92	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Liver	Cardiometabolic endpoints	Weighted median	12	0.10	0.04	1.58E-02	0.92	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Liver	Cardiometabolic endpoints	DIVW	12	0.14	0.03	8.86E-06	0.92	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Liver	Cardiometabolic endpoints	GRAPPLE	12	0.13	0.05	5.75E-03	0.92	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Liver	Cardiometabolic endpoints	mr_raps	12	0.13	0.03	1.14E-04	0.92	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Senile cataract	Liver	VII Diseases of the eye and adnexa (H7_)	MR Egger	12	-0.09	0.08	3.09E-01	0.29	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Senile cataract	Liver	VII Diseases of the eye and adnexa (H7_)	Inverse variance weighted (fixed effects)	12	-0.16	0.03	7.73E-08	0.29	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Senile cataract	Liver	VII Diseases of the eye and adnexa (H7_)	Inverse variance weighted (multiplicative random effects)	12	-0.16	0.06	4.12E-03	0.29	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Senile cataract	Liver	VII Diseases of the eye and adnexa (H7_)	Weighted mode	12	-0.12	0.04	1.46E-02	0.29	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Senile cataract	Liver	VII Diseases of the eye and adnexa (H7_)	Weighted median	12	-0.13	0.04	5.31E-04	0.29	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Senile cataract	Liver	VII Diseases of the eye and adnexa (H7_)	DIVW	12	-0.16	0.03	4.76E-08	0.29	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Senile cataract	Liver	VII Diseases of the eye and adnexa (H7_)	GRAPPLE	12	-0.14	0.05	3.12E-03	0.29	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Senile cataract	Liver	VII Diseases of the eye and adnexa (H7_)	mr_raps	12	-0.15	0.03	2.48E-06	0.29	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of choroid and retina	Liver	VII Diseases of the eye and adnexa (H7_)	MR Egger	12	0.03	0.08	7.24E-01	0.01	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of choroid and retina	Liver	VII Diseases of the eye and adnexa (H7_)	Inverse variance weighted (fixed effects)	12	-0.16	0.03	9.37E-07	0.01	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of choroid and retina	Liver	VII Diseases of the eye and adnexa (H7_)	Inverse variance weighted (multiplicative random effects)	12	-0.16	0.07	2.60E-02	0.01	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of choroid and retina	Liver	VII Diseases of the eye and adnexa (H7_)	Weighted mode	12	-0.07	0.04	1.38E-01	0.01	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of choroid and retina	Liver	VII Diseases of the eye and adnexa (H7_)	Weighted median	12	-0.06	0.04	1.83E-01	0.01	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of choroid and retina	Liver	VII Diseases of the eye and adnexa (H7_)	DIVW	12	-0.16	0.03	5.41E-07	0.01	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of choroid and retina	Liver	VII Diseases of the eye and adnexa (H7_)	GRAPPLE	12	-0.12	0.06	5.97E-02	0.01	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of choroid and retina	Liver	VII Diseases of the eye and adnexa (H7_)	mr_raps	12	-0.13	0.03	1.42E-04	0.01	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of the eye and adnexa	Liver	VII Diseases of the eye and adnexa (H7_)	MR Egger	12	0.00	0.07	9.49E-01	0.03	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of the eye and adnexa	Liver	VII Diseases of the eye and adnexa (H7_)	Inverse variance weighted (fixed effects)	12	-0.12	0.02	5.05E-10	0.03	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of the eye and adnexa	Liver	VII Diseases of the eye and adnexa (H7_)	Inverse variance weighted (multiplicative random effects)	12	-0.12	0.05	2.61E-02	0.03	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of the eye and adnexa	Liver	VII Diseases of the eye and adnexa (H7_)	Weighted mode	12	-0.05	0.02	4.80E-02	0.03	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of the eye and adnexa	Liver	VII Diseases of the eye and adnexa (H7_)	Weighted median	12	-0.05	0.02	3.24E-02	0.03	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of the eye and adnexa	Liver	VII Diseases of the eye and adnexa (H7_)	DIVW	12	-0.12	0.02	3.64E-10	0.03	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of the eye and adnexa	Liver	VII Diseases of the eye and adnexa (H7_)	GRAPPLE	12	-0.08	0.04	3.28E-02	0.03	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of the eye and adnexa	Liver	VII Diseases of the eye and adnexa (H7_)	mr_raps	12	-0.08	0.02	1.41E-05	0.03	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of lens	Liver	VII Diseases of the eye and adnexa (H7_)	MR Egger	12	-0.07	0.08	4.07E-01	0.24	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of lens	Liver	VII Diseases of the eye and adnexa (H7_)	Inverse variance weighted (fixed effects)	12	-0.15	0.03	2.30E-07	0.24	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of lens	Liver	VII Diseases of the eye and adnexa (H7_)	Inverse variance weighted (multiplicative random effects)	12	-0.15	0.06	7.71E-03	0.24	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of lens	Liver	VII Diseases of the eye and adnexa (H7_)	Weighted mode	12	-0.09	0.04	2.76E-02	0.24	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of lens	Liver	VII Diseases of the eye and adnexa (H7_)	Weighted median	12	-0.10	0.04	4.32E-03	0.24	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of lens	Liver	VII Diseases of the eye and adnexa (H7_)	DIVW	12	-0.15	0.03	1.37E-07	0.24	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of lens	Liver	VII Diseases of the eye and adnexa (H7_)	GRAPPLE	12	-0.12	0.05	7.13E-03	0.24	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of lens	Liver	VII Diseases of the eye and adnexa (H7_)	mr_raps	12	-0.13	0.03	1.69E-05	0.24	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of sclera, cornea, iris and ciliary body	Liver	VII Diseases of the eye and adnexa (H7_)	MR Egger	12	0.01	0.24	9.75E-01	0.35	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of sclera, cornea, iris and ciliary body	Liver	VII Diseases of the eye and adnexa (H7_)	Inverse variance weighted (fixed effects)	12	-0.17	0.04	3.43E-05	0.35	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of sclera, cornea, iris and ciliary body	Liver	VII Diseases of the eye and adnexa (H7_)	Inverse variance weighted (multiplicative random effects)	12	-0.17	0.16	2.91E-01	0.35	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of sclera, cornea, iris and ciliary body	Liver	VII Diseases of the eye and adnexa (H7_)	Weighted mode	12	-0.07	0.05	2.06E-01	0.35	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of sclera, cornea, iris and ciliary body	Liver	VII Diseases of the eye and adnexa (H7_)	Weighted median	12	-0.07	0.05	1.47E-01	0.35	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of sclera, cornea, iris and ciliary body	Liver	VII Diseases of the eye and adnexa (H7_)	DIVW	12	-0.17	0.04	1.85E-05	0.35	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of sclera, cornea, iris and ciliary body	Liver	VII Diseases of the eye and adnexa (H7_)	GRAPPLE	12	-0.08	0.10	4.00E-01	0.35	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Disorders of sclera, cornea, iris and ciliary body	Liver	VII Diseases of the eye and adnexa (H7_)	mr_raps	12	-0.06	0.04	1.17E-01	0.35	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Atrial fibrillation and flutter	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	12	0.21	0.06	4.48E-03	0.21	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Atrial fibrillation and flutter	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	12	0.15	0.04	5.42E-05	0.21	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Atrial fibrillation and flutter	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	12	0.15	0.04	1.10E-04	0.21	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Atrial fibrillation and flutter	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	12	0.19	0.05	2.85E-03	0.21	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Atrial fibrillation and flutter	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	12	0.17	0.05	3.02E-04	0.21	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Atrial fibrillation and flutter	Liver	IX Diseases of the circulatory system (I9_)	DIVW	12	0.15	0.04	2.90E-05	0.21	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Atrial fibrillation and flutter	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	12	0.16	0.04	8.16E-05	0.21	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Atrial fibrillation and flutter	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	12	0.15	0.04	6.41E-05	0.21	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	12	0.10	0.06	1.56E-01	0.74	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	12	0.11	0.03	1.08E-05	0.74	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	12	0.11	0.04	4.89E-03	0.74	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	12	0.09	0.03	1.90E-02	0.74	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	12	0.07	0.03	3.85E-02	0.74	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Liver	IX Diseases of the circulatory system (I9_)	DIVW	12	0.12	0.03	5.93E-06	0.74	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	12	0.11	0.04	6.41E-03	0.74	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	12	0.12	0.03	1.65E-05	0.74	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	MR Egger	12	-0.06	0.05	2.98E-01	0.23	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	12	-0.11	0.02	3.09E-07	0.23	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	12	-0.11	0.04	2.58E-03	0.23	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Weighted mode	12	-0.09	0.03	1.32E-02	0.23	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	Weighted median	12	-0.07	0.03	1.33E-02	0.23	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	DIVW	12	-0.11	0.02	1.83E-07	0.23	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	GRAPPLE	12	-0.09	0.03	8.10E-03	0.23	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Liver iron content	Statin medication	Liver	IX Diseases of the circulatory system (I9_)	mr_raps	12	-0.10	0.02	3.28E-06	0.23	rs115380467,rs11969981,rs12525479,rs151726,rs1799945,rs2523990,rs3819406,rs7383537,rs7577758,rs80215559,rs855791,rs9467711
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas	Cardiometabolic endpoints	MR Egger	7	2.45	1.53	1.70E-01	0.22	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas	Cardiometabolic endpoints	Inverse variance weighted (fixed effects)	7	0.36	0.06	9.03E-10	0.22	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas	Cardiometabolic endpoints	Inverse variance weighted (multiplicative random effects)	7	0.36	0.30	2.33E-01	0.22	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas	Cardiometabolic endpoints	Weighted mode	7	0.12	0.11	2.95E-01	0.22	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas	Cardiometabolic endpoints	Weighted median	7	0.13	0.09	1.71E-01	0.22	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas	Cardiometabolic endpoints	DIVW	7	0.37	0.06	2.94E-09	0.22	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas	Cardiometabolic endpoints	GRAPPLE	7	0.28	0.33	3.91E-01	0.22	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas	Cardiometabolic endpoints	mr_raps	7	0.16	0.05	1.10E-03	0.22	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Pulmonary heart disease	Pancreas	Cardiometabolic endpoints	MR Egger	7	2.04	2.47	4.45E-01	0.61	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Pulmonary heart disease	Pancreas	Cardiometabolic endpoints	Inverse variance weighted (fixed effects)	7	0.74	0.11	1.20E-11	0.61	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Pulmonary heart disease	Pancreas	Cardiometabolic endpoints	Inverse variance weighted (multiplicative random effects)	7	0.74	0.43	8.32E-02	0.61	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Pulmonary heart disease	Pancreas	Cardiometabolic endpoints	Weighted mode	7	0.30	0.17	1.32E-01	0.61	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Pulmonary heart disease	Pancreas	Cardiometabolic endpoints	Weighted median	7	0.26	0.15	9.05E-02	0.61	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Pulmonary heart disease	Pancreas	Cardiometabolic endpoints	DIVW	7	0.75	0.12	9.37E-11	0.61	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Pulmonary heart disease	Pancreas	Cardiometabolic endpoints	GRAPPLE	7	0.59	0.45	1.88E-01	0.61	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Pulmonary heart disease	Pancreas	Cardiometabolic endpoints	mr_raps	7	0.40	0.10	4.73E-05	0.61	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Pancreas	IX Diseases of the circulatory system (I9_)	MR Egger	7	2.12	1.33	1.71E-01	0.23	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Pancreas	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	7	0.33	0.05	4.04E-12	0.23	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Pancreas	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	7	0.33	0.26	2.01E-01	0.23	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Pancreas	IX Diseases of the circulatory system (I9_)	Weighted mode	7	0.12	0.09	2.53E-01	0.23	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Pancreas	IX Diseases of the circulatory system (I9_)	Weighted median	7	0.12	0.09	1.52E-01	0.23	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Pancreas	IX Diseases of the circulatory system (I9_)	DIVW	7	0.34	0.05	3.98E-11	0.23	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Pancreas	IX Diseases of the circulatory system (I9_)	GRAPPLE	7	0.29	0.29	3.18E-01	0.23	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	Pancreas	IX Diseases of the circulatory system (I9_)	mr_raps	7	0.23	0.04	2.42E-08	0.23	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	DVT of lower extremities and pulmonary embolism	Pancreas	IX Diseases of the circulatory system (I9_)	MR Egger	7	3.27	2.68	2.77E-01	0.40	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	DVT of lower extremities and pulmonary embolism	Pancreas	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	7	0.87	0.08	8.89E-27	0.40	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	DVT of lower extremities and pulmonary embolism	Pancreas	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	7	0.87	0.49	7.43E-02	0.40	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	DVT of lower extremities and pulmonary embolism	Pancreas	IX Diseases of the circulatory system (I9_)	Weighted mode	7	0.37	0.14	3.91E-02	0.40	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	DVT of lower extremities and pulmonary embolism	Pancreas	IX Diseases of the circulatory system (I9_)	Weighted median	7	0.39	0.12	1.41E-03	0.40	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	DVT of lower extremities and pulmonary embolism	Pancreas	IX Diseases of the circulatory system (I9_)	DIVW	7	0.88	0.10	0.00E+00	0.40	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	DVT of lower extremities and pulmonary embolism	Pancreas	IX Diseases of the circulatory system (I9_)	GRAPPLE	7	0.68	0.51	1.80E-01	0.40	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	DVT of lower extremities and pulmonary embolism	Pancreas	IX Diseases of the circulatory system (I9_)	mr_raps	7	0.46	0.06	1.04E-12	0.40	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Statin medication	Pancreas	IX Diseases of the circulatory system (I9_)	MR Egger	7	0.78	1.35	5.90E-01	0.70	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Statin medication	Pancreas	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (fixed effects)	7	0.23	0.04	3.74E-09	0.70	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Statin medication	Pancreas	IX Diseases of the circulatory system (I9_)	Inverse variance weighted (multiplicative random effects)	7	0.23	0.23	3.12E-01	0.70	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Statin medication	Pancreas	IX Diseases of the circulatory system (I9_)	Weighted mode	7	-0.08	0.06	2.07E-01	0.70	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Statin medication	Pancreas	IX Diseases of the circulatory system (I9_)	Weighted median	7	-0.06	0.06	3.44E-01	0.70	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Statin medication	Pancreas	IX Diseases of the circulatory system (I9_)	DIVW	7	0.24	0.04	9.45E-09	0.70	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Statin medication	Pancreas	IX Diseases of the circulatory system (I9_)	GRAPPLE	7	0.17	0.25	4.98E-01	0.70	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380
Pancreas fat	Statin medication	Pancreas	IX Diseases of the circulatory system (I9_)	mr_raps	7	0.02	0.03	5.70E-01	0.70	rs10422861,rs115478735,rs11679492,rs2066319,rs4733612,rs6489511,rs7405380

id.exposure	id.outcome	exp.category	out.category	method	nsnp	b	se	pval	MR.Egger.intercept pvalue	snps
Autoimmune diseases	Spleen volume	Diseases marked as autimmune origin	Spleen	MR Egger	133	0.11	0.04	1.40E-02	0.39	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Spleen volume	Diseases marked as autimmune origin	Spleen	Inverse variance weighted (fixed effects)	133	0.08	0.01	1.93E-12	0.39	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Spleen volume	Diseases marked as autimmune origin	Spleen	Inverse variance weighted (multiplicative random effects)	133	0.08	0.02	1.07E-03	0.39	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Spleen volume	Diseases marked as autimmune origin	Spleen	Weighted mode	133	0.06	0.02	4.48E-03	0.39	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Spleen volume	Diseases marked as autimmune origin	Spleen	Weighted median	133	0.06	0.02	9.02E-03	0.39	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Spleen volume	Diseases marked as autimmune origin	Spleen	DIVW	133	0.08	0.01	1.09E-12	0.39	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Spleen volume	Diseases marked as autimmune origin	Spleen	GRAPPLE	133	0.04	0.02	3.42E-02	0.39	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Spleen volume	Diseases marked as autimmune origin	Spleen	mr_raps	133	0.05	0.01	9.56E-06	0.39	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Liver iron content	Diseases marked as autimmune origin	Liver	MR Egger	133	-0.09	0.04	2.70E-02	0.29	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Liver iron content	Diseases marked as autimmune origin	Liver	Inverse variance weighted (fixed effects)	133	-0.05	0.01	1.46E-05	0.29	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Liver iron content	Diseases marked as autimmune origin	Liver	Inverse variance weighted (multiplicative random effects)	133	-0.05	0.02	1.24E-02	0.29	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Liver iron content	Diseases marked as autimmune origin	Liver	Weighted mode	133	-0.08	0.02	9.13E-04	0.29	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Liver iron content	Diseases marked as autimmune origin	Liver	Weighted median	133	-0.06	0.02	2.02E-03	0.29	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Liver iron content	Diseases marked as autimmune origin	Liver	DIVW	133	-0.05	0.01	7.43E-06	0.29	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Liver iron content	Diseases marked as autimmune origin	Liver	GRAPPLE	133	-0.05	0.02	5.40E-03	0.29	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Autoimmune diseases	Liver iron content	Diseases marked as autimmune origin	Liver	mr_raps	133	-0.05	0.01	1.36E-04	0.29	rs1042174,rs10456425,rs10481413,rs10484565,rs10739580,rs10748781,rs10758594,rs10795791,rs11244,rs115017884,rs115194949,rs11571297,rs11611847,rs11631591,rs116495604,rs11675342,rs11729055,rs117810449,rs117853452,rs12136119,rs1216538,rs12189725,rs12354257,rs12410532,rs12730973,rs12928537,rs13105678,rs13197513,rs13300483,rs1347001,rs140967207,rs144631938,rs145496147,rs150420498,rs151215234,rs151233,rs1534430,rs1790588,rs184535943,rs191875864,rs1980496,rs1990760,rs1993945,rs199762200,rs2004640,rs2066634,rs206763,rs2148907,rs2208397,rs2258734,rs229526,rs2396083,rs2476601,rs2477239,rs2774290,rs28579922,rs2983511,rs3094680,rs310772,rs3130248,rs3184504,rs34236350,rs34536443,rs35916594,rs35956754,rs3798544,rs3842753,rs3861929,rs3963512,rs41295119,rs4256430,rs4359051,rs4367411,rs4409785,rs4594881,rs4686955,rs4796664,rs479777,rs4839307,rs4853458,rs56204359,rs5757599,rs60026049,rs603985,rs60600003,rs62397626,rs62432712,rs6457718,rs6545846,rs659805,rs6724363,rs6762648,rs6828814,rs6908626,rs6982966,rs6990534,rs71641308,rs720465,rs7237497,rs7254729,rs72831263,rs72980748,rs73188832,rs73316435,rs73666889,rs7520823,rs75329808,rs7567564,rs76169968,rs76433928,rs77241188,rs773112,rs77708900,rs78954994,rs7902146,rs79866453,rs8081264,rs8098858,rs8193,rs85139,rs86703,rs914960,rs925488,rs9261441,rs9267325,rs927986,rs932036,rs9393698,rs9466083,rs952579,rs9557205,rs9594368,rs9975418
Mental and behavioural disorders due to alcohol	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	MR Egger	6	0.15	0.05	3.26E-02	0.55	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (fixed effects)	6	0.13	0.03	2.69E-07	0.55	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (multiplicative random effects)	6	0.13	0.03	1.18E-04	0.55	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Weighted mode	6	0.14	0.03	9.63E-03	0.55	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Weighted median	6	0.13	0.03	4.71E-05	0.55	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	DIVW	6	0.13	0.03	2.81E-06	0.55	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	GRAPPLE	6	0.13	0.03	3.55E-05	0.55	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	mr_raps	6	0.13	0.03	6.80E-06	0.55	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Pancreas fat	V Mental and behavioural disorders (F5_)	Pancreas	MR Egger	6	0.08	0.04	1.01E-01	0.60	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Pancreas fat	V Mental and behavioural disorders (F5_)	Pancreas	Inverse variance weighted (fixed effects)	6	0.09	0.03	1.35E-03	0.60	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Pancreas fat	V Mental and behavioural disorders (F5_)	Pancreas	Inverse variance weighted (multiplicative random effects)	6	0.09	0.01	2.68E-09	0.60	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Pancreas fat	V Mental and behavioural disorders (F5_)	Pancreas	Weighted mode	6	0.08	0.04	8.69E-02	0.60	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Pancreas fat	V Mental and behavioural disorders (F5_)	Pancreas	Weighted median	6	0.09	0.03	6.33E-03	0.60	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Pancreas fat	V Mental and behavioural disorders (F5_)	Pancreas	DIVW	6	0.09	0.03	1.18E-03	0.60	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Pancreas fat	V Mental and behavioural disorders (F5_)	Pancreas	GRAPPLE	6	0.09	0.03	2.58E-03	0.60	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Mental and behavioural disorders due to alcohol	Pancreas fat	V Mental and behavioural disorders (F5_)	Pancreas	mr_raps	6	0.09	0.03	3.69E-03	0.60	rs10828184,rs1229984,rs17586163,rs34768045,rs6738911,rs6773417
Dementia, including avohilmo	Liver volume	V Mental and behavioural disorders (F5_)	Liver	MR Egger	10	-0.15	0.04	9.08E-03	0.51	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (fixed effects)	10	-0.13	0.02	1.65E-09	0.51	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (multiplicative random effects)	10	-0.13	0.03	4.08E-06	0.51	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Weighted mode	10	-0.13	0.03	7.27E-04	0.51	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Weighted median	10	-0.13	0.02	1.39E-07	0.51	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Liver volume	V Mental and behavioural disorders (F5_)	Liver	DIVW	10	-0.13	0.02	1.31E-09	0.51	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Liver volume	V Mental and behavioural disorders (F5_)	Liver	GRAPPLE	10	-0.13	0.03	8.33E-05	0.51	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Liver volume	V Mental and behavioural disorders (F5_)	Liver	mr_raps	10	-0.13	0.02	2.67E-09	0.51	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Visceral adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	MR Egger	10	-0.08	0.03	4.03E-02	0.99	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Visceral adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	Inverse variance weighted (fixed effects)	10	-0.08	0.02	1.70E-04	0.99	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Visceral adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	Inverse variance weighted (multiplicative random effects)	10	-0.08	0.01	7.53E-15	0.99	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Visceral adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	Weighted mode	10	-0.08	0.02	1.37E-02	0.99	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Visceral adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	Weighted median	10	-0.08	0.02	9.25E-04	0.99	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Visceral adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	DIVW	10	-0.08	0.02	9.15E-05	0.99	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Visceral adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	GRAPPLE	10	-0.08	0.02	2.71E-04	0.99	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Visceral adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	mr_raps	10	-0.08	0.02	2.99E-04	0.99	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Abdominal subcutaneous adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	MR Egger	10	-0.06	0.03	1.04E-01	0.61	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Abdominal subcutaneous adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	Inverse variance weighted (fixed effects)	10	-0.08	0.02	5.39E-04	0.61	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Abdominal subcutaneous adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	Inverse variance weighted (multiplicative random effects)	10	-0.08	0.02	3.13E-05	0.61	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Abdominal subcutaneous adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	Weighted mode	10	-0.07	0.03	2.87E-02	0.61	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Abdominal subcutaneous adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	Weighted median	10	-0.06	0.02	9.07E-03	0.61	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Abdominal subcutaneous adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	DIVW	10	-0.08	0.02	2.84E-04	0.61	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Abdominal subcutaneous adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	GRAPPLE	10	-0.07	0.02	1.03E-03	0.61	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Abdominal subcutaneous adipose tissue measurement	V Mental and behavioural disorders (F5_)	Adipose tissue	mr_raps	10	-0.07	0.02	1.01E-03	0.61	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	MR Egger	10	-0.34	0.06	3.54E-04	0.13	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (fixed effects)	10	-0.27	0.02	5.85E-30	0.13	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (multiplicative random effects)	10	-0.27	0.04	9.52E-11	0.13	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Weighted mode	10	-0.31	0.03	2.96E-06	0.13	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Weighted median	10	-0.29	0.03	2.12E-21	0.13	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	DIVW	10	-0.27	0.02	0.00E+00	0.13	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	GRAPPLE	10	-0.24	0.05	4.59E-07	0.13	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia, including avohilmo	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	mr_raps	10	-0.27	0.03	0.00E+00	0.13	rs10406980,rs11666698,rs12610524,rs183110257,rs2199575,rs344819,rs41542613,rs429358,rs5167,rs8111560
Dementia	Liver volume	V Mental and behavioural disorders (F5_)	Liver	MR Egger	25	-0.08	0.02	5.15E-05	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (fixed effects)	25	-0.04	0.01	9.73E-06	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (multiplicative random effects)	25	-0.04	0.01	9.46E-04	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Weighted mode	25	-0.05	0.01	1.04E-04	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Weighted median	25	-0.05	0.01	3.76E-06	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Liver volume	V Mental and behavioural disorders (F5_)	Liver	DIVW	25	-0.04	0.01	5.22E-06	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Liver volume	V Mental and behavioural disorders (F5_)	Liver	GRAPPLE	25	-0.04	0.01	1.27E-03	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Liver volume	V Mental and behavioural disorders (F5_)	Liver	mr_raps	25	-0.04	0.01	4.29E-06	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	MR Egger	25	-0.15	0.02	3.76E-09	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (fixed effects)	25	-0.09	0.01	4.96E-19	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (multiplicative random effects)	25	-0.09	0.01	8.89E-09	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Weighted mode	25	-0.12	0.01	3.89E-09	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Weighted median	25	-0.12	0.01	4.74E-16	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	DIVW	25	-0.09	0.01	0.00E+00	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	GRAPPLE	25	-0.07	0.02	1.12E-05	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Dementia	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	mr_raps	25	-0.06	0.01	1.54E-10	0.00	rs11880899,rs12972282,rs12980519,rs143399042,rs146680240,rs16943758,rs16980815,rs183110257,rs183336979,rs2060245,rs344819,rs368745,rs4803744,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs62116949,rs7232,rs76222888,rs7982,rs8111560,rs8113128,rs9912362
Psychiatric diseases	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	MR Egger	12	-1.07	0.16	6.63E-05	0.00	rs12700986,rs2069191,rs2186800,rs419055,rs429358,rs4357651,rs4619804,rs5167,rs61340731,rs7004305,rs77431211,rs9467714
Psychiatric diseases	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (fixed effects)	12	-0.32	0.05	6.64E-12	0.00	rs12700986,rs2069191,rs2186800,rs419055,rs429358,rs4357651,rs4619804,rs5167,rs61340731,rs7004305,rs77431211,rs9467714
Psychiatric diseases	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (multiplicative random effects)	12	-0.32	0.14	2.46E-02	0.00	rs12700986,rs2069191,rs2186800,rs419055,rs429358,rs4357651,rs4619804,rs5167,rs61340731,rs7004305,rs77431211,rs9467714
Psychiatric diseases	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Weighted mode	12	-0.01	0.11	9.00E-01	0.00	rs12700986,rs2069191,rs2186800,rs419055,rs429358,rs4357651,rs4619804,rs5167,rs61340731,rs7004305,rs77431211,rs9467714
Psychiatric diseases	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Weighted median	12	-0.14	0.10	1.69E-01	0.00	rs12700986,rs2069191,rs2186800,rs419055,rs429358,rs4357651,rs4619804,rs5167,rs61340731,rs7004305,rs77431211,rs9467714
Psychiatric diseases	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	DIVW	12	-0.33	0.05	1.63E-11	0.00	rs12700986,rs2069191,rs2186800,rs419055,rs429358,rs4357651,rs4619804,rs5167,rs61340731,rs7004305,rs77431211,rs9467714
Psychiatric diseases	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	GRAPPLE	12	0.06	0.13	6.29E-01	0.00	rs12700986,rs2069191,rs2186800,rs419055,rs429358,rs4357651,rs4619804,rs5167,rs61340731,rs7004305,rs77431211,rs9467714
Psychiatric diseases	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	mr_raps	12	-0.07	0.05	1.01E-01	0.00	rs12700986,rs2069191,rs2186800,rs419055,rs429358,rs4357651,rs4619804,rs5167,rs61340731,rs7004305,rs77431211,rs9467714
Mental and behavioural disorders due to psychoctive substance use	Liver volume	V Mental and behavioural disorders (F5_)	Liver	MR Egger	6	0.04	0.04	4.11E-01	0.68	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (fixed effects)	6	0.06	0.03	6.76E-02	0.68	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (multiplicative random effects)	6	0.06	0.01	1.20E-07	0.68	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Weighted mode	6	0.05	0.04	2.78E-01	0.68	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Liver volume	V Mental and behavioural disorders (F5_)	Liver	Weighted median	6	0.05	0.04	1.91E-01	0.68	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Liver volume	V Mental and behavioural disorders (F5_)	Liver	DIVW	6	0.06	0.03	3.66E-02	0.68	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Liver volume	V Mental and behavioural disorders (F5_)	Liver	GRAPPLE	6	0.06	0.03	7.94E-02	0.68	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Liver volume	V Mental and behavioural disorders (F5_)	Liver	mr_raps	6	0.06	0.03	9.24E-02	0.68	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	MR Egger	6	0.24	0.05	8.15E-03	0.06	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (fixed effects)	6	0.15	0.03	8.78E-06	0.06	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Inverse variance weighted (multiplicative random effects)	6	0.15	0.04	5.00E-04	0.06	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Weighted mode	6	0.21	0.05	9.95E-03	0.06	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	Weighted median	6	0.13	0.05	1.19E-02	0.06	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	DIVW	6	0.15	0.04	3.22E-05	0.06	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	GRAPPLE	6	0.16	0.04	2.54E-04	0.06	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Mental and behavioural disorders due to psychoctive substance use	Percent Liver fat	V Mental and behavioural disorders (F5_)	Liver	mr_raps	6	0.15	0.04	6.32E-05	0.06	rs10828184,rs1229984,rs17586163,rs2186800,rs419055,rs7756952
Alzheimer‚Äôs disease, wide definition	Liver volume	VI Diseases of the nervous system (G6_)	Liver	MR Egger	27	-0.06	0.01	3.07E-05	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	27	-0.03	0.01	1.19E-05	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	27	-0.03	0.01	3.07E-04	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	27	-0.05	0.01	1.73E-04	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted median	27	-0.05	0.01	3.65E-06	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Liver volume	VI Diseases of the nervous system (G6_)	Liver	DIVW	27	-0.03	0.01	6.32E-06	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Liver volume	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	27	-0.03	0.01	7.45E-04	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Liver volume	VI Diseases of the nervous system (G6_)	Liver	mr_raps	27	-0.03	0.01	4.58E-05	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	MR Egger	27	-0.13	0.01	2.57E-09	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	27	-0.08	0.01	3.81E-23	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	27	-0.08	0.01	2.69E-11	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	27	-0.11	0.01	1.01E-09	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Weighted median	27	-0.10	0.01	2.05E-15	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	DIVW	27	-0.08	0.01	0.00E+00	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	27	-0.07	0.01	9.57E-08	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer‚Äôs disease, wide definition	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	mr_raps	27	-0.06	0.01	3.33E-15	0.00	rs10423934,rs11881956,rs12972282,rs147412235,rs183110257,rs183336979,rs2060245,rs2119660,rs2341634,rs2682565,rs2965112,rs344819,rs397133,rs41542613,rs449647,rs5167,rs56317818,rs5848,rs59007384,rs62116949,rs7232,rs7255066,rs75727214,rs8111560,rs8113128,rs846890,rs9615051
Alzheimer disease	Liver volume	VI Diseases of the nervous system (G6_)	Liver	MR Egger	22	-0.06	0.01	5.62E-05	0.00	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	22	-0.03	0.01	2.16E-05	0.00	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	22	-0.03	0.01	6.29E-04	0.00	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	22	-0.04	0.01	3.51E-04	0.00	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted median	22	-0.05	0.01	3.46E-06	0.00	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Liver volume	VI Diseases of the nervous system (G6_)	Liver	DIVW	22	-0.03	0.01	1.15E-05	0.00	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Liver volume	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	22	-0.03	0.01	9.43E-04	0.00	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Liver volume	VI Diseases of the nervous system (G6_)	Liver	mr_raps	22	-0.03	0.01	1.99E-04	0.00	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	MR Egger	22	-0.02	0.01	5.94E-02	0.83	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (fixed effects)	22	-0.03	0.01	1.58E-04	0.83	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (multiplicative random effects)	22	-0.03	0.01	3.18E-05	0.83	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted mode	22	-0.03	0.01	8.98E-03	0.83	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted median	22	-0.02	0.01	6.04E-03	0.83	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	DIVW	22	-0.03	0.01	8.21E-05	0.83	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	GRAPPLE	22	-0.03	0.01	3.04E-04	0.83	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	mr_raps	22	-0.03	0.01	3.19E-04	0.83	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	MR Egger	22	-0.13	0.02	5.21E-07	0.01	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	22	-0.09	0.01	1.03E-27	0.01	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	22	-0.09	0.01	1.69E-13	0.01	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	22	-0.11	0.01	9.78E-10	0.01	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Weighted median	22	-0.10	0.01	1.34E-18	0.01	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	DIVW	22	-0.09	0.01	0.00E+00	0.01	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	22	-0.09	0.01	8.10E-13	0.01	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Alzheimer disease	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	mr_raps	22	-0.08	0.01	0.00E+00	0.01	rs10405859,rs10419906,rs10423934,rs10469272,rs12974310,rs143399042,rs183110257,rs183336979,rs1995850,rs2682565,rs2927438,rs2972558,rs344819,rs449647,rs5167,rs56158216,rs59007384,rs62116949,rs7232,rs744373,rs75750038,rs846887
Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas volume	Cardiometabolic endpoints	Pancreas	MR Egger	41	-0.07	0.07	3.61E-01	0.89	rs10429966,rs11121615,rs11583606,rs11589479,rs117468318,rs12740371,rs13143677,rs1363561,rs148491338,rs1657686,rs17255424,rs2010667,rs2013002,rs2066865,rs2105382,rs2189759,rs2250127,rs236524,rs284278,rs340836,rs35156964,rs3738814,rs3740357,rs3756011,rs3787184,rs4296409,rs474534,rs4845948,rs6025,rs6062618,rs635634,rs71646941,rs7308872,rs7547686,rs764326,rs7910776,rs7937758,rs80325942,rs9505897,rs9880192,rs9922619
Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas volume	Cardiometabolic endpoints	Pancreas	Inverse variance weighted (fixed effects)	41	-0.08	0.02	1.16E-05	0.89	rs10429966,rs11121615,rs11583606,rs11589479,rs117468318,rs12740371,rs13143677,rs1363561,rs148491338,rs1657686,rs17255424,rs2010667,rs2013002,rs2066865,rs2105382,rs2189759,rs2250127,rs236524,rs284278,rs340836,rs35156964,rs3738814,rs3740357,rs3756011,rs3787184,rs4296409,rs474534,rs4845948,rs6025,rs6062618,rs635634,rs71646941,rs7308872,rs7547686,rs764326,rs7910776,rs7937758,rs80325942,rs9505897,rs9880192,rs9922619
Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas volume	Cardiometabolic endpoints	Pancreas	Inverse variance weighted (multiplicative random effects)	41	-0.08	0.03	1.10E-02	0.89	rs10429966,rs11121615,rs11583606,rs11589479,rs117468318,rs12740371,rs13143677,rs1363561,rs148491338,rs1657686,rs17255424,rs2010667,rs2013002,rs2066865,rs2105382,rs2189759,rs2250127,rs236524,rs284278,rs340836,rs35156964,rs3738814,rs3740357,rs3756011,rs3787184,rs4296409,rs474534,rs4845948,rs6025,rs6062618,rs635634,rs71646941,rs7308872,rs7547686,rs764326,rs7910776,rs7937758,rs80325942,rs9505897,rs9880192,rs9922619
Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas volume	Cardiometabolic endpoints	Pancreas	Weighted mode	41	-0.01	0.03	7.84E-01	0.89	rs10429966,rs11121615,rs11583606,rs11589479,rs117468318,rs12740371,rs13143677,rs1363561,rs148491338,rs1657686,rs17255424,rs2010667,rs2013002,rs2066865,rs2105382,rs2189759,rs2250127,rs236524,rs284278,rs340836,rs35156964,rs3738814,rs3740357,rs3756011,rs3787184,rs4296409,rs474534,rs4845948,rs6025,rs6062618,rs635634,rs71646941,rs7308872,rs7547686,rs764326,rs7910776,rs7937758,rs80325942,rs9505897,rs9880192,rs9922619
Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas volume	Cardiometabolic endpoints	Pancreas	Weighted median	41	-0.02	0.03	4.50E-01	0.89	rs10429966,rs11121615,rs11583606,rs11589479,rs117468318,rs12740371,rs13143677,rs1363561,rs148491338,rs1657686,rs17255424,rs2010667,rs2013002,rs2066865,rs2105382,rs2189759,rs2250127,rs236524,rs284278,rs340836,rs35156964,rs3738814,rs3740357,rs3756011,rs3787184,rs4296409,rs474534,rs4845948,rs6025,rs6062618,rs635634,rs71646941,rs7308872,rs7547686,rs764326,rs7910776,rs7937758,rs80325942,rs9505897,rs9880192,rs9922619
Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas volume	Cardiometabolic endpoints	Pancreas	DIVW	41	-0.08	0.02	6.40E-06	0.89	rs10429966,rs11121615,rs11583606,rs11589479,rs117468318,rs12740371,rs13143677,rs1363561,rs148491338,rs1657686,rs17255424,rs2010667,rs2013002,rs2066865,rs2105382,rs2189759,rs2250127,rs236524,rs284278,rs340836,rs35156964,rs3738814,rs3740357,rs3756011,rs3787184,rs4296409,rs474534,rs4845948,rs6025,rs6062618,rs635634,rs71646941,rs7308872,rs7547686,rs764326,rs7910776,rs7937758,rs80325942,rs9505897,rs9880192,rs9922619
Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas volume	Cardiometabolic endpoints	Pancreas	GRAPPLE	41	-0.03	0.03	2.59E-01	0.89	rs10429966,rs11121615,rs11583606,rs11589479,rs117468318,rs12740371,rs13143677,rs1363561,rs148491338,rs1657686,rs17255424,rs2010667,rs2013002,rs2066865,rs2105382,rs2189759,rs2250127,rs236524,rs284278,rs340836,rs35156964,rs3738814,rs3740357,rs3756011,rs3787184,rs4296409,rs474534,rs4845948,rs6025,rs6062618,rs635634,rs71646941,rs7308872,rs7547686,rs764326,rs7910776,rs7937758,rs80325942,rs9505897,rs9880192,rs9922619
Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)	Pancreas volume	Cardiometabolic endpoints	Pancreas	mr_raps	41	-0.05	0.02	8.31E-03	0.89	rs10429966,rs11121615,rs11583606,rs11589479,rs117468318,rs12740371,rs13143677,rs1363561,rs148491338,rs1657686,rs17255424,rs2010667,rs2013002,rs2066865,rs2105382,rs2189759,rs2250127,rs236524,rs284278,rs340836,rs35156964,rs3738814,rs3740357,rs3756011,rs3787184,rs4296409,rs474534,rs4845948,rs6025,rs6062618,rs635634,rs71646941,rs7308872,rs7547686,rs764326,rs7910776,rs7937758,rs80325942,rs9505897,rs9880192,rs9922619
Alzheimer disease, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	MR Egger	27	-0.07	0.01	9.82E-06	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	27	-0.03	0.01	2.51E-04	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	27	-0.03	0.01	5.68E-03	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	27	-0.04	0.01	1.38E-04	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted median	27	-0.04	0.01	1.86E-05	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	DIVW	27	-0.03	0.01	1.29E-04	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	27	-0.03	0.01	7.32E-03	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	mr_raps	27	-0.02	0.01	4.84E-03	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	MR Egger	27	-0.13	0.02	2.32E-08	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	27	-0.08	0.01	1.06E-22	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	27	-0.08	0.01	1.15E-10	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	27	-0.11	0.01	5.62E-09	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Weighted median	27	-0.10	0.01	1.18E-14	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	DIVW	27	-0.08	0.01	0.00E+00	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	27	-0.07	0.01	1.91E-08	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Alzheimer disease, including avohilmo	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	mr_raps	27	-0.06	0.01	5.55E-15	0.00	rs10423934,rs12972094,rs143399042,rs183110257,rs183336979,rs1995850,rs204539,rs2060245,rs2119660,rs2341634,rs2682565,rs344819,rs41542613,rs440277,rs449647,rs5167,rs55972177,rs56158216,rs5848,rs59007384,rs6115847,rs62116949,rs6733839,rs7232,rs8111560,rs8113128,rs846887
Nerve, nerve root and plexus disorders	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	MR Egger	8	-1.29	0.60	7.56E-02	0.04	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (fixed effects)	8	0.26	0.06	2.76E-06	0.04	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (multiplicative random effects)	8	0.26	0.19	1.62E-01	0.04	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted mode	8	0.10	0.08	2.27E-01	0.04	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted median	8	0.10	0.08	2.10E-01	0.04	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	DIVW	8	0.27	0.06	3.28E-06	0.04	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	GRAPPLE	8	0.11	0.18	5.49E-01	0.04	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	mr_raps	8	0.17	0.05	8.72E-04	0.04	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Liver iron content	VI Diseases of the nervous system (G6_)	Liver	MR Egger	8	-0.80	0.74	3.20E-01	0.46	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Liver iron content	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	8	-0.23	0.06	9.62E-05	0.46	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Liver iron content	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	8	-0.23	0.16	1.55E-01	0.46	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Liver iron content	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	8	-0.29	0.20	1.87E-01	0.46	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Liver iron content	VI Diseases of the nervous system (G6_)	Liver	Weighted median	8	-0.23	0.11	4.16E-02	0.46	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Liver iron content	VI Diseases of the nervous system (G6_)	Liver	DIVW	8	-0.24	0.06	7.40E-05	0.46	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Liver iron content	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	8	-0.25	0.19	1.97E-01	0.46	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Nerve, nerve root and plexus disorders	Liver iron content	VI Diseases of the nervous system (G6_)	Liver	mr_raps	8	-0.29	0.06	3.23E-06	0.46	rs1121980,rs11583952,rs1383258,rs1720021,rs4959105,rs72836480,rs73082331,rs9273367
Neurological diseases	Lung volume	VI Diseases of the nervous system (G6_)	Lung	MR Egger	6	0.23	0.62	7.37E-01	0.80	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Lung volume	VI Diseases of the nervous system (G6_)	Lung	Inverse variance weighted (fixed effects)	6	0.39	0.09	4.30E-06	0.80	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Lung volume	VI Diseases of the nervous system (G6_)	Lung	Inverse variance weighted (multiplicative random effects)	6	0.39	0.04	1.60E-25	0.80	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Lung volume	VI Diseases of the nervous system (G6_)	Lung	Weighted mode	6	0.35	0.15	6.59E-02	0.80	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Lung volume	VI Diseases of the nervous system (G6_)	Lung	Weighted median	6	0.36	0.10	5.20E-04	0.80	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Lung volume	VI Diseases of the nervous system (G6_)	Lung	DIVW	6	0.41	0.09	6.24E-06	0.80	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Lung volume	VI Diseases of the nervous system (G6_)	Lung	GRAPPLE	6	0.40	0.09	1.96E-05	0.80	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Lung volume	VI Diseases of the nervous system (G6_)	Lung	mr_raps	6	0.40	0.10	3.58E-05	0.80	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	MR Egger	6	-1.17	0.61	1.30E-01	0.28	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (fixed effects)	6	-0.40	0.08	1.81E-06	0.28	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (multiplicative random effects)	6	-0.40	0.05	1.26E-15	0.28	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted mode	6	-0.33	0.16	8.97E-02	0.28	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted median	6	-0.37	0.11	4.53E-04	0.28	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	DIVW	6	-0.41	0.09	3.09E-06	0.28	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	GRAPPLE	6	-0.40	0.09	1.12E-05	0.28	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	mr_raps	6	-0.41	0.09	1.71E-05	0.28	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	MR Egger	6	-6.79	1.27	5.86E-03	0.01	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	6	-0.75	0.10	1.72E-14	0.01	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	6	-0.75	0.41	6.28E-02	0.01	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	6	-0.31	0.16	1.12E-01	0.01	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Weighted median	6	-0.34	0.14	1.32E-02	0.01	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	DIVW	6	-0.78	0.12	8.20E-12	0.01	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	6	-0.78	0.48	1.06E-01	0.01	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Neurological diseases	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	mr_raps	6	-0.43	0.09	1.32E-06	0.01	rs10416513,rs1273044,rs2233679,rs2249741,rs429358,rs68164957
Other degenerative diseases of the nervous system	Liver volume	VI Diseases of the nervous system (G6_)	Liver	MR Egger	20	-0.07	0.01	6.30E-05	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	20	-0.03	0.01	6.41E-05	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	20	-0.03	0.01	1.31E-03	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	20	-0.05	0.01	1.82E-04	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted median	20	-0.05	0.01	1.85E-05	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Liver volume	VI Diseases of the nervous system (G6_)	Liver	DIVW	20	-0.03	0.01	3.40E-05	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Liver volume	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	20	-0.04	0.01	2.20E-04	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Liver volume	VI Diseases of the nervous system (G6_)	Liver	mr_raps	20	-0.04	0.01	2.18E-05	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	MR Egger	20	-0.15	0.02	8.56E-08	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	20	-0.09	0.01	1.26E-21	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	20	-0.09	0.02	1.28E-07	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	20	-0.13	0.01	3.97E-08	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	Weighted median	20	-0.11	0.02	1.66E-13	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	DIVW	20	-0.09	0.01	0.00E+00	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	20	-0.10	0.02	2.47E-08	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Other degenerative diseases of the nervous system	Percent Liver fat	VI Diseases of the nervous system (G6_)	Liver	mr_raps	20	-0.07	0.01	2.18E-13	0.00	rs10419906,rs10469272,rs1081105,rs11878174,rs12976241,rs143399042,rs2060245,rs2682544,rs344819,rs419010,rs4500861,rs50871,rs55972177,rs7232,rs7253845,rs7257625,rs7412,rs769449,rs8111388,rs846887
Sleep apnoea	Liver volume	VI Diseases of the nervous system (G6_)	Liver	MR Egger	8	0.62	0.32	9.82E-02	0.21	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	8	0.18	0.04	2.80E-05	0.21	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	8	0.18	0.08	2.13E-02	0.21	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	8	0.14	0.11	2.33E-01	0.21	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted median	8	0.17	0.07	1.96E-02	0.21	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Liver volume	VI Diseases of the nervous system (G6_)	Liver	DIVW	8	0.19	0.05	2.39E-05	0.21	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Liver volume	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	8	0.11	0.09	2.26E-01	0.21	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Liver volume	VI Diseases of the nervous system (G6_)	Liver	mr_raps	8	0.15	0.05	9.21E-04	0.21	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	MR Egger	8	0.57	0.25	5.86E-02	0.20	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	Inverse variance weighted (fixed effects)	8	0.23	0.04	5.48E-09	0.20	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	Inverse variance weighted (multiplicative random effects)	8	0.23	0.06	1.93E-04	0.20	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	Weighted mode	8	0.31	0.07	2.75E-03	0.20	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	Weighted median	8	0.28	0.06	2.57E-06	0.20	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	DIVW	8	0.24	0.04	1.76E-08	0.20	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	GRAPPLE	8	0.24	0.06	1.26E-04	0.20	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	mr_raps	8	0.27	0.04	1.67E-09	0.20	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	MR Egger	8	0.59	0.28	8.35E-02	0.19	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (fixed effects)	8	0.18	0.04	1.85E-05	0.19	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (multiplicative random effects)	8	0.18	0.07	1.45E-02	0.19	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted mode	8	0.29	0.08	8.84E-03	0.19	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted median	8	0.20	0.07	3.75E-03	0.19	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	DIVW	8	0.18	0.04	1.65E-05	0.19	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	GRAPPLE	8	0.14	0.08	7.25E-02	0.19	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	mr_raps	8	0.17	0.04	9.14E-05	0.19	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	MR Egger	8	1.05	0.47	6.64E-02	0.16	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (fixed effects)	8	0.31	0.04	4.68E-12	0.16	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (multiplicative random effects)	8	0.31	0.12	1.12E-02	0.16	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted mode	8	0.21	0.10	6.90E-02	0.16	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted median	8	0.23	0.07	2.62E-03	0.16	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	DIVW	8	0.32	0.05	7.73E-11	0.16	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	GRAPPLE	8	0.16	0.14	2.74E-01	0.16	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	mr_raps	8	0.20	0.04	3.93E-06	0.16	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	MR Egger	8	-0.32	0.23	2.13E-01	0.61	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	Inverse variance weighted (fixed effects)	8	-0.20	0.05	2.01E-04	0.61	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	Inverse variance weighted (multiplicative random effects)	8	-0.20	0.04	1.37E-07	0.61	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	Weighted mode	8	-0.23	0.08	3.25E-02	0.61	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	Weighted median	8	-0.21	0.07	4.30E-03	0.61	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	DIVW	8	-0.21	0.06	1.41E-04	0.61	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	GRAPPLE	8	-0.20	0.06	4.26E-04	0.61	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	mr_raps	8	-0.20	0.06	5.33E-04	0.61	rs10125995,rs10507084,rs12511115,rs142006783,rs6791437,rs742760,rs76229479,rs9937053
Sleep apnoea, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	MR Egger	13	0.19	0.25	4.47E-01	0.87	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (fixed effects)	13	0.15	0.04	2.51E-05	0.87	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Inverse variance weighted (multiplicative random effects)	13	0.15	0.06	6.06E-03	0.87	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted mode	13	0.10	0.10	3.51E-01	0.87	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	Weighted median	13	0.12	0.06	4.68E-02	0.87	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	DIVW	13	0.16	0.04	1.86E-05	0.87	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	GRAPPLE	13	0.11	0.06	7.89E-02	0.87	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Liver volume	VI Diseases of the nervous system (G6_)	Liver	mr_raps	13	0.13	0.04	9.09E-04	0.87	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	MR Egger	13	0.55	0.21	2.58E-02	0.08	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	Inverse variance weighted (fixed effects)	13	0.15	0.03	6.02E-06	0.08	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	Inverse variance weighted (multiplicative random effects)	13	0.15	0.06	8.28E-03	0.08	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	Weighted mode	13	0.17	0.13	2.18E-01	0.08	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	Weighted median	13	0.17	0.06	3.12E-03	0.08	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	DIVW	13	0.15	0.03	5.02E-06	0.08	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	GRAPPLE	13	0.15	0.05	6.86E-03	0.08	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Kidney volume	VI Diseases of the nervous system (G6_)	Kidney	mr_raps	13	0.16	0.03	5.04E-06	0.08	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	MR Egger	13	0.20	0.25	4.36E-01	0.82	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (fixed effects)	13	0.14	0.03	2.52E-05	0.82	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (multiplicative random effects)	13	0.14	0.06	1.09E-02	0.82	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted mode	13	0.31	0.16	8.39E-02	0.82	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted median	13	0.13	0.06	4.01E-02	0.82	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	DIVW	13	0.15	0.04	1.86E-05	0.82	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	GRAPPLE	13	0.10	0.06	6.86E-02	0.82	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Visceral adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	mr_raps	13	0.13	0.04	1.94E-04	0.82	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	MR Egger	13	0.49	0.37	2.16E-01	0.52	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (fixed effects)	13	0.25	0.04	5.40E-11	0.52	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Inverse variance weighted (multiplicative random effects)	13	0.25	0.09	4.23E-03	0.52	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted mode	13	0.16	0.09	1.02E-01	0.52	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	Weighted median	13	0.14	0.06	1.63E-02	0.52	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	DIVW	13	0.25	0.04	2.21E-10	0.52	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	GRAPPLE	13	0.12	0.08	1.45E-01	0.52	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Abdominal subcutaneous adipose tissue measurement	VI Diseases of the nervous system (G6_)	Adipose tissue	mr_raps	13	0.17	0.04	7.17E-06	0.52	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	MR Egger	13	-0.22	0.19	2.77E-01	0.76	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	Inverse variance weighted (fixed effects)	13	-0.16	0.05	3.90E-04	0.76	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	Inverse variance weighted (multiplicative random effects)	13	-0.16	0.03	2.54E-06	0.76	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	Weighted mode	13	-0.18	0.09	6.47E-02	0.76	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	Weighted median	13	-0.15	0.06	1.19E-02	0.76	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	DIVW	13	-0.16	0.05	2.39E-04	0.76	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	GRAPPLE	13	-0.16	0.05	7.40E-04	0.76	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Sleep apnoea, including avohilmo	Pancreas iron content	VI Diseases of the nervous system (G6_)	Pancreas	mr_raps	13	-0.16	0.05	9.39E-04	0.76	rs10125995,rs1023230,rs10507084,rs12511115,rs12698822,rs142006783,rs1637366,rs2137605,rs28838737,rs4809902,rs76229479,rs7824549,rs9937053
Disorders of choroid and retina	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	MR Egger	22	-0.09	0.07	2.22E-01	0.72	rs10456405,rs10922098,rs149340530,rs2476601,rs28397274,rs28479464,rs3094640,rs3128918,rs3750846,rs3842753,rs3957146,rs41268932,rs444921,rs59356242,rs6585819,rs6903171,rs6914780,rs7071419,rs7118363,rs72750531,rs72848740,rs9276710
Disorders of choroid and retina	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	Inverse variance weighted (fixed effects)	22	-0.11	0.02	5.30E-12	0.72	rs10456405,rs10922098,rs149340530,rs2476601,rs28397274,rs28479464,rs3094640,rs3128918,rs3750846,rs3842753,rs3957146,rs41268932,rs444921,rs59356242,rs6585819,rs6903171,rs6914780,rs7071419,rs7118363,rs72750531,rs72848740,rs9276710
Disorders of choroid and retina	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	Inverse variance weighted (multiplicative random effects)	22	-0.11	0.03	1.09E-03	0.72	rs10456405,rs10922098,rs149340530,rs2476601,rs28397274,rs28479464,rs3094640,rs3128918,rs3750846,rs3842753,rs3957146,rs41268932,rs444921,rs59356242,rs6585819,rs6903171,rs6914780,rs7071419,rs7118363,rs72750531,rs72848740,rs9276710
Disorders of choroid and retina	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	Weighted mode	22	-0.14	0.03	6.48E-05	0.72	rs10456405,rs10922098,rs149340530,rs2476601,rs28397274,rs28479464,rs3094640,rs3128918,rs3750846,rs3842753,rs3957146,rs41268932,rs444921,rs59356242,rs6585819,rs6903171,rs6914780,rs7071419,rs7118363,rs72750531,rs72848740,rs9276710
Disorders of choroid and retina	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	Weighted median	22	-0.13	0.03	4.66E-07	0.72	rs10456405,rs10922098,rs149340530,rs2476601,rs28397274,rs28479464,rs3094640,rs3128918,rs3750846,rs3842753,rs3957146,rs41268932,rs444921,rs59356242,rs6585819,rs6903171,rs6914780,rs7071419,rs7118363,rs72750531,rs72848740,rs9276710
Disorders of choroid and retina	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	DIVW	22	-0.11	0.02	4.24E-12	0.72	rs10456405,rs10922098,rs149340530,rs2476601,rs28397274,rs28479464,rs3094640,rs3128918,rs3750846,rs3842753,rs3957146,rs41268932,rs444921,rs59356242,rs6585819,rs6903171,rs6914780,rs7071419,rs7118363,rs72750531,rs72848740,rs9276710
Disorders of choroid and retina	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	GRAPPLE	22	-0.10	0.03	6.43E-04	0.72	rs10456405,rs10922098,rs149340530,rs2476601,rs28397274,rs28479464,rs3094640,rs3128918,rs3750846,rs3842753,rs3957146,rs41268932,rs444921,rs59356242,rs6585819,rs6903171,rs6914780,rs7071419,rs7118363,rs72750531,rs72848740,rs9276710
Disorders of choroid and retina	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	mr_raps	22	-0.12	0.02	1.21E-12	0.72	rs10456405,rs10922098,rs149340530,rs2476601,rs28397274,rs28479464,rs3094640,rs3128918,rs3750846,rs3842753,rs3957146,rs41268932,rs444921,rs59356242,rs6585819,rs6903171,rs6914780,rs7071419,rs7118363,rs72750531,rs72848740,rs9276710
Conjunctivitis	Spleen volume	VII Diseases of the eye and adnexa (H7_)	Spleen	MR Egger	6	1.14	1.76	5.52E-01	0.43	rs11065979,rs11751024,rs4936444,rs62395355,rs72823641,rs9493981
Conjunctivitis	Spleen volume	VII Diseases of the eye and adnexa (H7_)	Spleen	Inverse variance weighted (fixed effects)	6	-0.36	0.05	1.68E-14	0.43	rs11065979,rs11751024,rs4936444,rs62395355,rs72823641,rs9493981
Conjunctivitis	Spleen volume	VII Diseases of the eye and adnexa (H7_)	Spleen	Inverse variance weighted (multiplicative random effects)	6	-0.36	0.34	2.82E-01	0.43	rs11065979,rs11751024,rs4936444,rs62395355,rs72823641,rs9493981
Conjunctivitis	Spleen volume	VII Diseases of the eye and adnexa (H7_)	Spleen	Weighted mode	6	-0.10	0.07	2.25E-01	0.43	rs11065979,rs11751024,rs4936444,rs62395355,rs72823641,rs9493981
Conjunctivitis	Spleen volume	VII Diseases of the eye and adnexa (H7_)	Spleen	Weighted median	6	-0.07	0.07	2.89E-01	0.43	rs11065979,rs11751024,rs4936444,rs62395355,rs72823641,rs9493981
Conjunctivitis	Spleen volume	VII Diseases of the eye and adnexa (H7_)	Spleen	DIVW	6	-0.37	0.06	1.04E-11	0.43	rs11065979,rs11751024,rs4936444,rs62395355,rs72823641,rs9493981
Conjunctivitis	Spleen volume	VII Diseases of the eye and adnexa (H7_)	Spleen	GRAPPLE	6	-0.21	0.28	4.68E-01	0.43	rs11065979,rs11751024,rs4936444,rs62395355,rs72823641,rs9493981
Conjunctivitis	Spleen volume	VII Diseases of the eye and adnexa (H7_)	Spleen	mr_raps	6	-1.78	0.25	3.81E-13	0.43	rs11065979,rs11751024,rs4936444,rs62395355,rs72823641,rs9493981
Diseases of the eye and adnexa	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	MR Egger	17	-0.40	0.25	1.35E-01	0.37	rs10484565,rs11244,rs1126504,rs113486274,rs17341179,rs2516721,rs3742015,rs4263621,rs429358,rs4713175,rs4814857,rs6690982,rs6941972,rs72834689,rs79299723,rs9267283,rs9837662
Diseases of the eye and adnexa	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	Inverse variance weighted (fixed effects)	17	-0.18	0.04	4.96E-05	0.37	rs10484565,rs11244,rs1126504,rs113486274,rs17341179,rs2516721,rs3742015,rs4263621,rs429358,rs4713175,rs4814857,rs6690982,rs6941972,rs72834689,rs79299723,rs9267283,rs9837662
Diseases of the eye and adnexa	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	Inverse variance weighted (multiplicative random effects)	17	-0.18	0.10	5.75E-02	0.37	rs10484565,rs11244,rs1126504,rs113486274,rs17341179,rs2516721,rs3742015,rs4263621,rs429358,rs4713175,rs4814857,rs6690982,rs6941972,rs72834689,rs79299723,rs9267283,rs9837662
Diseases of the eye and adnexa	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	Weighted mode	17	-0.38	0.18	4.95E-02	0.37	rs10484565,rs11244,rs1126504,rs113486274,rs17341179,rs2516721,rs3742015,rs4263621,rs429358,rs4713175,rs4814857,rs6690982,rs6941972,rs72834689,rs79299723,rs9267283,rs9837662
Diseases of the eye and adnexa	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	Weighted median	17	-0.28	0.09	1.13E-03	0.37	rs10484565,rs11244,rs1126504,rs113486274,rs17341179,rs2516721,rs3742015,rs4263621,rs429358,rs4713175,rs4814857,rs6690982,rs6941972,rs72834689,rs79299723,rs9267283,rs9837662
Diseases of the eye and adnexa	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	DIVW	17	-0.19	0.05	2.97E-05	0.37	rs10484565,rs11244,rs1126504,rs113486274,rs17341179,rs2516721,rs3742015,rs4263621,rs429358,rs4713175,rs4814857,rs6690982,rs6941972,rs72834689,rs79299723,rs9267283,rs9837662
Diseases of the eye and adnexa	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	GRAPPLE	17	-0.15	0.10	1.30E-01	0.37	rs10484565,rs11244,rs1126504,rs113486274,rs17341179,rs2516721,rs3742015,rs4263621,rs429358,rs4713175,rs4814857,rs6690982,rs6941972,rs72834689,rs79299723,rs9267283,rs9837662
Diseases of the eye and adnexa	Liver iron content	VII Diseases of the eye and adnexa (H7_)	Liver	mr_raps	17	-0.19	0.05	6.25E-05	0.37	rs10484565,rs11244,rs1126504,rs113486274,rs17341179,rs2516721,rs3742015,rs4263621,rs429358,rs4713175,rs4814857,rs6690982,rs6941972,rs72834689,rs79299723,rs9267283,rs9837662
Atherosclerosis, excluding cerebral, coronary and PAD	Pancreas iron content	IX Diseases of the circulatory system (I9_)	Pancreas	MR Egger	11	0.07	0.10	4.89E-01	0.71	rs11633958,rs118039278,rs17248727,rs2107595,rs244419,rs2727271,rs75697049,rs915896,rs9273364,rs9295128,rs9644862
Atherosclerosis, excluding cerebral, coronary and PAD	Pancreas iron content	IX Diseases of the circulatory system (I9_)	Pancreas	Inverse variance weighted (fixed effects)	11	0.10	0.03	1.00E-04	0.71	rs11633958,rs118039278,rs17248727,rs2107595,rs244419,rs2727271,rs75697049,rs915896,rs9273364,rs9295128,rs9644862
Atherosclerosis, excluding cerebral, coronary and PAD	Pancreas iron content	IX Diseases of the circulatory system (I9_)	Pancreas	Inverse variance weighted (multiplicative random effects)	11	0.10	0.02	1.20E-10	0.71	rs11633958,rs118039278,rs17248727,rs2107595,rs244419,rs2727271,rs75697049,rs915896,rs9273364,rs9295128,rs9644862
Atherosclerosis, excluding cerebral, coronary and PAD	Pancreas iron content	IX Diseases of the circulatory system (I9_)	Pancreas	Weighted mode	11	0.07	0.05	1.66E-01	0.71	rs11633958,rs118039278,rs17248727,rs2107595,rs244419,rs2727271,rs75697049,rs915896,rs9273364,rs9295128,rs9644862
Atherosclerosis, excluding cerebral, coronary and PAD	Pancreas iron content	IX Diseases of the circulatory system (I9_)	Pancreas	Weighted median	11	0.09	0.03	6.45E-03	0.71	rs11633958,rs118039278,rs17248727,rs2107595,rs244419,rs2727271,rs75697049,rs915896,rs9273364,rs9295128,rs9644862
Atherosclerosis, excluding cerebral, coronary and PAD	Pancreas iron content	IX Diseases of the circulatory system (I9_)	Pancreas	DIVW	11	0.11	0.03	6.52E-05	0.71	rs11633958,rs118039278,rs17248727,rs2107595,rs244419,rs2727271,rs75697049,rs915896,rs9273364,rs9295128,rs9644862
Atherosclerosis, excluding cerebral, coronary and PAD	Pancreas iron content	IX Diseases of the circulatory system (I9_)	Pancreas	GRAPPLE	11	0.10	0.03	2.03E-04	0.71	rs11633958,rs118039278,rs17248727,rs2107595,rs244419,rs2727271,rs75697049,rs915896,rs9273364,rs9295128,rs9644862
Atherosclerosis, excluding cerebral, coronary and PAD	Pancreas iron content	IX Diseases of the circulatory system (I9_)	Pancreas	mr_raps	11	0.10	0.03	2.65E-04	0.71	rs11633958,rs118039278,rs17248727,rs2107595,rs244419,rs2727271,rs75697049,rs915896,rs9273364,rs9295128,rs9644862
Major coronary heart disease event	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	MR Egger	53	-0.06	0.11	6.01E-01	0.21	rs10402946,rs10431974,rs1044506,rs10455872,rs10811665,rs10945646,rs10965106,rs11238794,rs113113862,rs11591147,rs11617955,rs117733303,rs1199338,rs1208256,rs12438645,rs12474528,rs12941836,rs13134800,rs137943060,rs17110517,rs17114046,rs17163301,rs17411045,rs1835346,rs2044474,rs2107595,rs28451064,rs28605759,rs2954017,rs35166119,rs3918226,rs4350997,rs494198,rs5344,rs6119534,rs62341322,rs629301,rs653178,rs67370089,rs6892439,rs6946226,rs7036656,rs7158073,rs72749233,rs7412,rs7500448,rs7608755,rs7668383,rs77028772,rs78100181,rs9349379,rs9515203,rs964184
Major coronary heart disease event	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Inverse variance weighted (fixed effects)	53	0.07	0.01	5.55E-07	0.21	rs10402946,rs10431974,rs1044506,rs10455872,rs10811665,rs10945646,rs10965106,rs11238794,rs113113862,rs11591147,rs11617955,rs117733303,rs1199338,rs1208256,rs12438645,rs12474528,rs12941836,rs13134800,rs137943060,rs17110517,rs17114046,rs17163301,rs17411045,rs1835346,rs2044474,rs2107595,rs28451064,rs28605759,rs2954017,rs35166119,rs3918226,rs4350997,rs494198,rs5344,rs6119534,rs62341322,rs629301,rs653178,rs67370089,rs6892439,rs6946226,rs7036656,rs7158073,rs72749233,rs7412,rs7500448,rs7608755,rs7668383,rs77028772,rs78100181,rs9349379,rs9515203,rs964184
Major coronary heart disease event	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Inverse variance weighted (multiplicative random effects)	53	0.07	0.05	1.36E-01	0.21	rs10402946,rs10431974,rs1044506,rs10455872,rs10811665,rs10945646,rs10965106,rs11238794,rs113113862,rs11591147,rs11617955,rs117733303,rs1199338,rs1208256,rs12438645,rs12474528,rs12941836,rs13134800,rs137943060,rs17110517,rs17114046,rs17163301,rs17411045,rs1835346,rs2044474,rs2107595,rs28451064,rs28605759,rs2954017,rs35166119,rs3918226,rs4350997,rs494198,rs5344,rs6119534,rs62341322,rs629301,rs653178,rs67370089,rs6892439,rs6946226,rs7036656,rs7158073,rs72749233,rs7412,rs7500448,rs7608755,rs7668383,rs77028772,rs78100181,rs9349379,rs9515203,rs964184
Major coronary heart disease event	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Weighted mode	53	-0.01	0.03	7.65E-01	0.21	rs10402946,rs10431974,rs1044506,rs10455872,rs10811665,rs10945646,rs10965106,rs11238794,rs113113862,rs11591147,rs11617955,rs117733303,rs1199338,rs1208256,rs12438645,rs12474528,rs12941836,rs13134800,rs137943060,rs17110517,rs17114046,rs17163301,rs17411045,rs1835346,rs2044474,rs2107595,rs28451064,rs28605759,rs2954017,rs35166119,rs3918226,rs4350997,rs494198,rs5344,rs6119534,rs62341322,rs629301,rs653178,rs67370089,rs6892439,rs6946226,rs7036656,rs7158073,rs72749233,rs7412,rs7500448,rs7608755,rs7668383,rs77028772,rs78100181,rs9349379,rs9515203,rs964184
Major coronary heart disease event	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Weighted median	53	0.00	0.02	9.44E-01	0.21	rs10402946,rs10431974,rs1044506,rs10455872,rs10811665,rs10945646,rs10965106,rs11238794,rs113113862,rs11591147,rs11617955,rs117733303,rs1199338,rs1208256,rs12438645,rs12474528,rs12941836,rs13134800,rs137943060,rs17110517,rs17114046,rs17163301,rs17411045,rs1835346,rs2044474,rs2107595,rs28451064,rs28605759,rs2954017,rs35166119,rs3918226,rs4350997,rs494198,rs5344,rs6119534,rs62341322,rs629301,rs653178,rs67370089,rs6892439,rs6946226,rs7036656,rs7158073,rs72749233,rs7412,rs7500448,rs7608755,rs7668383,rs77028772,rs78100181,rs9349379,rs9515203,rs964184
Major coronary heart disease event	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	DIVW	53	0.07	0.01	3.16E-07	0.21	rs10402946,rs10431974,rs1044506,rs10455872,rs10811665,rs10945646,rs10965106,rs11238794,rs113113862,rs11591147,rs11617955,rs117733303,rs1199338,rs1208256,rs12438645,rs12474528,rs12941836,rs13134800,rs137943060,rs17110517,rs17114046,rs17163301,rs17411045,rs1835346,rs2044474,rs2107595,rs28451064,rs28605759,rs2954017,rs35166119,rs3918226,rs4350997,rs494198,rs5344,rs6119534,rs62341322,rs629301,rs653178,rs67370089,rs6892439,rs6946226,rs7036656,rs7158073,rs72749233,rs7412,rs7500448,rs7608755,rs7668383,rs77028772,rs78100181,rs9349379,rs9515203,rs964184
Major coronary heart disease event	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	GRAPPLE	53	0.01	0.02	7.51E-01	0.21	rs10402946,rs10431974,rs1044506,rs10455872,rs10811665,rs10945646,rs10965106,rs11238794,rs113113862,rs11591147,rs11617955,rs117733303,rs1199338,rs1208256,rs12438645,rs12474528,rs12941836,rs13134800,rs137943060,rs17110517,rs17114046,rs17163301,rs17411045,rs1835346,rs2044474,rs2107595,rs28451064,rs28605759,rs2954017,rs35166119,rs3918226,rs4350997,rs494198,rs5344,rs6119534,rs62341322,rs629301,rs653178,rs67370089,rs6892439,rs6946226,rs7036656,rs7158073,rs72749233,rs7412,rs7500448,rs7608755,rs7668383,rs77028772,rs78100181,rs9349379,rs9515203,rs964184
Major coronary heart disease event	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	mr_raps	53	0.02	0.01	2.01E-01	0.21	rs10402946,rs10431974,rs1044506,rs10455872,rs10811665,rs10945646,rs10965106,rs11238794,rs113113862,rs11591147,rs11617955,rs117733303,rs1199338,rs1208256,rs12438645,rs12474528,rs12941836,rs13134800,rs137943060,rs17110517,rs17114046,rs17163301,rs17411045,rs1835346,rs2044474,rs2107595,rs28451064,rs28605759,rs2954017,rs35166119,rs3918226,rs4350997,rs494198,rs5344,rs6119534,rs62341322,rs629301,rs653178,rs67370089,rs6892439,rs6946226,rs7036656,rs7158073,rs72749233,rs7412,rs7500448,rs7608755,rs7668383,rs77028772,rs78100181,rs9349379,rs9515203,rs964184
Coronary atherosclerosis	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	MR Egger	60	-0.01	0.08	9.17E-01	0.37	rs10431974,rs1044506,rs10455872,rs10774624,rs10811665,rs10945646,rs11170821,rs113113862,rs1133220,rs11591147,rs11619038,rs11635498,rs11698996,rs117733303,rs1199337,rs12447309,rs12705390,rs12901658,rs13134800,rs137943060,rs1384705,rs1423457,rs1429125,rs1537371,rs1568488,rs16942194,rs1763943,rs1822200,rs1835346,rs2000660,rs2002854,rs2027939,rs2107595,rs2246828,rs28451064,rs3005923,rs3741298,rs3829964,rs3918226,rs4835377,rs5344,rs553741,rs59877521,rs629301,rs6741243,rs6921231,rs7158073,rs7209564,rs72661887,rs72664324,rs72794188,rs7412,rs7478408,rs7608755,rs7659823,rs7774311,rs7860576,rs7995370,rs9349379,rs9515203
Coronary atherosclerosis	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Inverse variance weighted (fixed effects)	60	0.06	0.01	2.83E-06	0.37	rs10431974,rs1044506,rs10455872,rs10774624,rs10811665,rs10945646,rs11170821,rs113113862,rs1133220,rs11591147,rs11619038,rs11635498,rs11698996,rs117733303,rs1199337,rs12447309,rs12705390,rs12901658,rs13134800,rs137943060,rs1384705,rs1423457,rs1429125,rs1537371,rs1568488,rs16942194,rs1763943,rs1822200,rs1835346,rs2000660,rs2002854,rs2027939,rs2107595,rs2246828,rs28451064,rs3005923,rs3741298,rs3829964,rs3918226,rs4835377,rs5344,rs553741,rs59877521,rs629301,rs6741243,rs6921231,rs7158073,rs7209564,rs72661887,rs72664324,rs72794188,rs7412,rs7478408,rs7608755,rs7659823,rs7774311,rs7860576,rs7995370,rs9349379,rs9515203
Coronary atherosclerosis	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Inverse variance weighted (multiplicative random effects)	60	0.06	0.04	1.16E-01	0.37	rs10431974,rs1044506,rs10455872,rs10774624,rs10811665,rs10945646,rs11170821,rs113113862,rs1133220,rs11591147,rs11619038,rs11635498,rs11698996,rs117733303,rs1199337,rs12447309,rs12705390,rs12901658,rs13134800,rs137943060,rs1384705,rs1423457,rs1429125,rs1537371,rs1568488,rs16942194,rs1763943,rs1822200,rs1835346,rs2000660,rs2002854,rs2027939,rs2107595,rs2246828,rs28451064,rs3005923,rs3741298,rs3829964,rs3918226,rs4835377,rs5344,rs553741,rs59877521,rs629301,rs6741243,rs6921231,rs7158073,rs7209564,rs72661887,rs72664324,rs72794188,rs7412,rs7478408,rs7608755,rs7659823,rs7774311,rs7860576,rs7995370,rs9349379,rs9515203
Coronary atherosclerosis	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Weighted mode	60	0.00	0.02	8.81E-01	0.37	rs10431974,rs1044506,rs10455872,rs10774624,rs10811665,rs10945646,rs11170821,rs113113862,rs1133220,rs11591147,rs11619038,rs11635498,rs11698996,rs117733303,rs1199337,rs12447309,rs12705390,rs12901658,rs13134800,rs137943060,rs1384705,rs1423457,rs1429125,rs1537371,rs1568488,rs16942194,rs1763943,rs1822200,rs1835346,rs2000660,rs2002854,rs2027939,rs2107595,rs2246828,rs28451064,rs3005923,rs3741298,rs3829964,rs3918226,rs4835377,rs5344,rs553741,rs59877521,rs629301,rs6741243,rs6921231,rs7158073,rs7209564,rs72661887,rs72664324,rs72794188,rs7412,rs7478408,rs7608755,rs7659823,rs7774311,rs7860576,rs7995370,rs9349379,rs9515203
Coronary atherosclerosis	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Weighted median	60	0.01	0.02	7.98E-01	0.37	rs10431974,rs1044506,rs10455872,rs10774624,rs10811665,rs10945646,rs11170821,rs113113862,rs1133220,rs11591147,rs11619038,rs11635498,rs11698996,rs117733303,rs1199337,rs12447309,rs12705390,rs12901658,rs13134800,rs137943060,rs1384705,rs1423457,rs1429125,rs1537371,rs1568488,rs16942194,rs1763943,rs1822200,rs1835346,rs2000660,rs2002854,rs2027939,rs2107595,rs2246828,rs28451064,rs3005923,rs3741298,rs3829964,rs3918226,rs4835377,rs5344,rs553741,rs59877521,rs629301,rs6741243,rs6921231,rs7158073,rs7209564,rs72661887,rs72664324,rs72794188,rs7412,rs7478408,rs7608755,rs7659823,rs7774311,rs7860576,rs7995370,rs9349379,rs9515203
Coronary atherosclerosis	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	DIVW	60	0.06	0.01	1.53E-06	0.37	rs10431974,rs1044506,rs10455872,rs10774624,rs10811665,rs10945646,rs11170821,rs113113862,rs1133220,rs11591147,rs11619038,rs11635498,rs11698996,rs117733303,rs1199337,rs12447309,rs12705390,rs12901658,rs13134800,rs137943060,rs1384705,rs1423457,rs1429125,rs1537371,rs1568488,rs16942194,rs1763943,rs1822200,rs1835346,rs2000660,rs2002854,rs2027939,rs2107595,rs2246828,rs28451064,rs3005923,rs3741298,rs3829964,rs3918226,rs4835377,rs5344,rs553741,rs59877521,rs629301,rs6741243,rs6921231,rs7158073,rs7209564,rs72661887,rs72664324,rs72794188,rs7412,rs7478408,rs7608755,rs7659823,rs7774311,rs7860576,rs7995370,rs9349379,rs9515203
Coronary atherosclerosis	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	GRAPPLE	60	0.02	0.02	4.24E-01	0.37	rs10431974,rs1044506,rs10455872,rs10774624,rs10811665,rs10945646,rs11170821,rs113113862,rs1133220,rs11591147,rs11619038,rs11635498,rs11698996,rs117733303,rs1199337,rs12447309,rs12705390,rs12901658,rs13134800,rs137943060,rs1384705,rs1423457,rs1429125,rs1537371,rs1568488,rs16942194,rs1763943,rs1822200,rs1835346,rs2000660,rs2002854,rs2027939,rs2107595,rs2246828,rs28451064,rs3005923,rs3741298,rs3829964,rs3918226,rs4835377,rs5344,rs553741,rs59877521,rs629301,rs6741243,rs6921231,rs7158073,rs7209564,rs72661887,rs72664324,rs72794188,rs7412,rs7478408,rs7608755,rs7659823,rs7774311,rs7860576,rs7995370,rs9349379,rs9515203
Coronary atherosclerosis	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	mr_raps	60	0.02	0.01	1.58E-01	0.37	rs10431974,rs1044506,rs10455872,rs10774624,rs10811665,rs10945646,rs11170821,rs113113862,rs1133220,rs11591147,rs11619038,rs11635498,rs11698996,rs117733303,rs1199337,rs12447309,rs12705390,rs12901658,rs13134800,rs137943060,rs1384705,rs1423457,rs1429125,rs1537371,rs1568488,rs16942194,rs1763943,rs1822200,rs1835346,rs2000660,rs2002854,rs2027939,rs2107595,rs2246828,rs28451064,rs3005923,rs3741298,rs3829964,rs3918226,rs4835377,rs5344,rs553741,rs59877521,rs629301,rs6741243,rs6921231,rs7158073,rs7209564,rs72661887,rs72664324,rs72794188,rs7412,rs7478408,rs7608755,rs7659823,rs7774311,rs7860576,rs7995370,rs9349379,rs9515203
Heart failure and antihypertensive medication	Spleen volume	Cardiometabolic endpoints	Spleen	MR Egger	22	-0.23	0.31	4.58E-01	0.30	rs10774624,rs11126666,rs116951734,rs11774829,rs1214759,rs12418543,rs12426399,rs13118687,rs1333042,rs16998073,rs17042171,rs17608766,rs2327429,rs3131004,rs3176323,rs3770770,rs3918226,rs4324466,rs72699046,rs73073444,rs7680240,rs880315
Heart failure and antihypertensive medication	Spleen volume	Cardiometabolic endpoints	Spleen	Inverse variance weighted (fixed effects)	22	0.08	0.02	2.66E-06	0.30	rs10774624,rs11126666,rs116951734,rs11774829,rs1214759,rs12418543,rs12426399,rs13118687,rs1333042,rs16998073,rs17042171,rs17608766,rs2327429,rs3131004,rs3176323,rs3770770,rs3918226,rs4324466,rs72699046,rs73073444,rs7680240,rs880315
Heart failure and antihypertensive medication	Spleen volume	Cardiometabolic endpoints	Spleen	Inverse variance weighted (multiplicative random effects)	22	0.08	0.07	2.46E-01	0.30	rs10774624,rs11126666,rs116951734,rs11774829,rs1214759,rs12418543,rs12426399,rs13118687,rs1333042,rs16998073,rs17042171,rs17608766,rs2327429,rs3131004,rs3176323,rs3770770,rs3918226,rs4324466,rs72699046,rs73073444,rs7680240,rs880315
Heart failure and antihypertensive medication	Spleen volume	Cardiometabolic endpoints	Spleen	Weighted mode	22	0.00	0.04	9.28E-01	0.30	rs10774624,rs11126666,rs116951734,rs11774829,rs1214759,rs12418543,rs12426399,rs13118687,rs1333042,rs16998073,rs17042171,rs17608766,rs2327429,rs3131004,rs3176323,rs3770770,rs3918226,rs4324466,rs72699046,rs73073444,rs7680240,rs880315
Heart failure and antihypertensive medication	Spleen volume	Cardiometabolic endpoints	Spleen	Weighted median	22	0.01	0.03	7.75E-01	0.30	rs10774624,rs11126666,rs116951734,rs11774829,rs1214759,rs12418543,rs12426399,rs13118687,rs1333042,rs16998073,rs17042171,rs17608766,rs2327429,rs3131004,rs3176323,rs3770770,rs3918226,rs4324466,rs72699046,rs73073444,rs7680240,rs880315
Heart failure and antihypertensive medication	Spleen volume	Cardiometabolic endpoints	Spleen	DIVW	22	0.09	0.02	1.82E-06	0.30	rs10774624,rs11126666,rs116951734,rs11774829,rs1214759,rs12418543,rs12426399,rs13118687,rs1333042,rs16998073,rs17042171,rs17608766,rs2327429,rs3131004,rs3176323,rs3770770,rs3918226,rs4324466,rs72699046,rs73073444,rs7680240,rs880315
Heart failure and antihypertensive medication	Spleen volume	Cardiometabolic endpoints	Spleen	GRAPPLE	22	0.01	0.03	7.21E-01	0.30	rs10774624,rs11126666,rs116951734,rs11774829,rs1214759,rs12418543,rs12426399,rs13118687,rs1333042,rs16998073,rs17042171,rs17608766,rs2327429,rs3131004,rs3176323,rs3770770,rs3918226,rs4324466,rs72699046,rs73073444,rs7680240,rs880315
Heart failure and antihypertensive medication	Spleen volume	Cardiometabolic endpoints	Spleen	mr_raps	22	0.03	0.02	1.05E-01	0.30	rs10774624,rs11126666,rs116951734,rs11774829,rs1214759,rs12418543,rs12426399,rs13118687,rs1333042,rs16998073,rs17042171,rs17608766,rs2327429,rs3131004,rs3176323,rs3770770,rs3918226,rs4324466,rs72699046,rs73073444,rs7680240,rs880315
Ischemic heart diseases	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	MR Egger	53	-0.06	0.12	5.99E-01	0.23	rs10431974,rs1044506,rs10455872,rs10793514,rs10811665,rs10945646,rs10965106,rs113113862,rs11591147,rs11619038,rs11698996,rs117733303,rs1199337,rs12438645,rs12945851,rs13134800,rs137943060,rs1537371,rs1568488,rs16942194,rs17489268,rs1763943,rs1835346,rs2000660,rs207180,rs2107595,rs2128739,rs2188127,rs2392929,rs28451064,rs28533705,rs28673728,rs3741298,rs3918226,rs4350997,rs553741,rs59877521,rs629301,rs653178,rs6892439,rs7158073,rs72664324,rs72794188,rs72938315,rs73181271,rs73855809,rs7412,rs75500872,rs7668383,rs78536205,rs8034587,rs9349379,rs9515203
Ischemic heart diseases	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Inverse variance weighted (fixed effects)	53	0.07	0.02	2.62E-05	0.23	rs10431974,rs1044506,rs10455872,rs10793514,rs10811665,rs10945646,rs10965106,rs113113862,rs11591147,rs11619038,rs11698996,rs117733303,rs1199337,rs12438645,rs12945851,rs13134800,rs137943060,rs1537371,rs1568488,rs16942194,rs17489268,rs1763943,rs1835346,rs2000660,rs207180,rs2107595,rs2128739,rs2188127,rs2392929,rs28451064,rs28533705,rs28673728,rs3741298,rs3918226,rs4350997,rs553741,rs59877521,rs629301,rs653178,rs6892439,rs7158073,rs72664324,rs72794188,rs72938315,rs73181271,rs73855809,rs7412,rs75500872,rs7668383,rs78536205,rs8034587,rs9349379,rs9515203
Ischemic heart diseases	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Inverse variance weighted (multiplicative random effects)	53	0.07	0.05	1.95E-01	0.23	rs10431974,rs1044506,rs10455872,rs10793514,rs10811665,rs10945646,rs10965106,rs113113862,rs11591147,rs11619038,rs11698996,rs117733303,rs1199337,rs12438645,rs12945851,rs13134800,rs137943060,rs1537371,rs1568488,rs16942194,rs17489268,rs1763943,rs1835346,rs2000660,rs207180,rs2107595,rs2128739,rs2188127,rs2392929,rs28451064,rs28533705,rs28673728,rs3741298,rs3918226,rs4350997,rs553741,rs59877521,rs629301,rs653178,rs6892439,rs7158073,rs72664324,rs72794188,rs72938315,rs73181271,rs73855809,rs7412,rs75500872,rs7668383,rs78536205,rs8034587,rs9349379,rs9515203
Ischemic heart diseases	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Weighted mode	53	0.00	0.03	9.19E-01	0.23	rs10431974,rs1044506,rs10455872,rs10793514,rs10811665,rs10945646,rs10965106,rs113113862,rs11591147,rs11619038,rs11698996,rs117733303,rs1199337,rs12438645,rs12945851,rs13134800,rs137943060,rs1537371,rs1568488,rs16942194,rs17489268,rs1763943,rs1835346,rs2000660,rs207180,rs2107595,rs2128739,rs2188127,rs2392929,rs28451064,rs28533705,rs28673728,rs3741298,rs3918226,rs4350997,rs553741,rs59877521,rs629301,rs653178,rs6892439,rs7158073,rs72664324,rs72794188,rs72938315,rs73181271,rs73855809,rs7412,rs75500872,rs7668383,rs78536205,rs8034587,rs9349379,rs9515203
Ischemic heart diseases	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	Weighted median	53	0.01	0.03	6.66E-01	0.23	rs10431974,rs1044506,rs10455872,rs10793514,rs10811665,rs10945646,rs10965106,rs113113862,rs11591147,rs11619038,rs11698996,rs117733303,rs1199337,rs12438645,rs12945851,rs13134800,rs137943060,rs1537371,rs1568488,rs16942194,rs17489268,rs1763943,rs1835346,rs2000660,rs207180,rs2107595,rs2128739,rs2188127,rs2392929,rs28451064,rs28533705,rs28673728,rs3741298,rs3918226,rs4350997,rs553741,rs59877521,rs629301,rs653178,rs6892439,rs7158073,rs72664324,rs72794188,rs72938315,rs73181271,rs73855809,rs7412,rs75500872,rs7668383,rs78536205,rs8034587,rs9349379,rs9515203
Ischemic heart diseases	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	DIVW	53	0.07	0.02	1.39E-05	0.23	rs10431974,rs1044506,rs10455872,rs10793514,rs10811665,rs10945646,rs10965106,rs113113862,rs11591147,rs11619038,rs11698996,rs117733303,rs1199337,rs12438645,rs12945851,rs13134800,rs137943060,rs1537371,rs1568488,rs16942194,rs17489268,rs1763943,rs1835346,rs2000660,rs207180,rs2107595,rs2128739,rs2188127,rs2392929,rs28451064,rs28533705,rs28673728,rs3741298,rs3918226,rs4350997,rs553741,rs59877521,rs629301,rs653178,rs6892439,rs7158073,rs72664324,rs72794188,rs72938315,rs73181271,rs73855809,rs7412,rs75500872,rs7668383,rs78536205,rs8034587,rs9349379,rs9515203
Ischemic heart diseases	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	GRAPPLE	53	0.01	0.03	6.39E-01	0.23	rs10431974,rs1044506,rs10455872,rs10793514,rs10811665,rs10945646,rs10965106,rs113113862,rs11591147,rs11619038,rs11698996,rs117733303,rs1199337,rs12438645,rs12945851,rs13134800,rs137943060,rs1537371,rs1568488,rs16942194,rs17489268,rs1763943,rs1835346,rs2000660,rs207180,rs2107595,rs2128739,rs2188127,rs2392929,rs28451064,rs28533705,rs28673728,rs3741298,rs3918226,rs4350997,rs553741,rs59877521,rs629301,rs653178,rs6892439,rs7158073,rs72664324,rs72794188,rs72938315,rs73181271,rs73855809,rs7412,rs75500872,rs7668383,rs78536205,rs8034587,rs9349379,rs9515203
Ischemic heart diseases	Spleen volume	IX Diseases of the circulatory system (I9_)	Spleen	mr_raps	53	0.02	0.02	1.98E-01	0.23	rs10431974,rs1044506,rs10455872,rs10793514,rs10811665,rs10945646,rs10965106,rs113113862,rs11591147,rs11619038,rs11698996,rs117733303,rs1199337,rs12438645,rs12945851,rs13134800,rs137943060,rs1537371,rs1568488,rs16942194,rs17489268,rs1763943,rs1835346,rs2000660,rs207180,rs2107595,rs2128739,rs2188127,rs2392929,rs28451064,rs28533705,rs28673728,rs3741298,rs3918226,rs4350997,rs553741,rs59877521,rs629301,rs653178,rs6892439,rs7158073,rs72664324,rs72794188,rs72938315,rs73181271,rs73855809,rs7412,rs75500872,rs7668383,rs78536205,rs8034587,rs9349379,rs9515203
Gonarthrosis [arthrosis of knee](FG)	Liver volume	Rheuma endpoints	Liver	MR Egger	32	0.48	0.30	1.19E-01	0.24	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Liver volume	Rheuma endpoints	Liver	Inverse variance weighted (fixed effects)	32	0.13	0.02	7.67E-08	0.24	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Liver volume	Rheuma endpoints	Liver	Inverse variance weighted (multiplicative random effects)	32	0.13	0.05	8.24E-03	0.24	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Liver volume	Rheuma endpoints	Liver	Weighted mode	32	0.12	0.07	1.04E-01	0.24	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Liver volume	Rheuma endpoints	Liver	Weighted median	32	0.11	0.04	9.19E-03	0.24	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Liver volume	Rheuma endpoints	Liver	DIVW	32	0.13	0.02	5.53E-08	0.24	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Liver volume	Rheuma endpoints	Liver	GRAPPLE	32	0.14	0.05	5.07E-03	0.24	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Liver volume	Rheuma endpoints	Liver	mr_raps	32	0.13	0.02	4.91E-08	0.24	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Kidney volume	Rheuma endpoints	Kidney	MR Egger	32	0.22	0.27	4.23E-01	0.67	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Kidney volume	Rheuma endpoints	Kidney	Inverse variance weighted (fixed effects)	32	0.10	0.02	1.36E-06	0.67	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Kidney volume	Rheuma endpoints	Kidney	Inverse variance weighted (multiplicative random effects)	32	0.10	0.04	1.39E-02	0.67	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Kidney volume	Rheuma endpoints	Kidney	Weighted mode	32	0.16	0.06	1.23E-02	0.67	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Kidney volume	Rheuma endpoints	Kidney	Weighted median	32	0.09	0.04	1.02E-02	0.67	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Kidney volume	Rheuma endpoints	Kidney	DIVW	32	0.11	0.02	8.64E-07	0.67	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Kidney volume	Rheuma endpoints	Kidney	GRAPPLE	32	0.10	0.04	1.49E-02	0.67	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Kidney volume	Rheuma endpoints	Kidney	mr_raps	32	0.11	0.02	5.74E-07	0.67	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Abdominal subcutaneous adipose tissue measurement	Rheuma endpoints	Adipose tissue	MR Egger	32	0.38	0.31	2.43E-01	0.39	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Abdominal subcutaneous adipose tissue measurement	Rheuma endpoints	Adipose tissue	Inverse variance weighted (fixed effects)	32	0.10	0.02	1.71E-05	0.39	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Abdominal subcutaneous adipose tissue measurement	Rheuma endpoints	Adipose tissue	Inverse variance weighted (multiplicative random effects)	32	0.10	0.05	3.65E-02	0.39	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Abdominal subcutaneous adipose tissue measurement	Rheuma endpoints	Adipose tissue	Weighted mode	32	0.05	0.08	5.66E-01	0.39	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Abdominal subcutaneous adipose tissue measurement	Rheuma endpoints	Adipose tissue	Weighted median	32	0.06	0.04	9.17E-02	0.39	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Abdominal subcutaneous adipose tissue measurement	Rheuma endpoints	Adipose tissue	DIVW	32	0.11	0.02	9.96E-06	0.39	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Abdominal subcutaneous adipose tissue measurement	Rheuma endpoints	Adipose tissue	GRAPPLE	32	0.06	0.04	1.14E-01	0.39	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Gonarthrosis [arthrosis of knee](FG)	Abdominal subcutaneous adipose tissue measurement	Rheuma endpoints	Adipose tissue	mr_raps	32	0.07	0.02	6.27E-03	0.39	rs10131337,rs10408721,rs10817111,rs10859587,rs1242997,rs12684080,rs12706012,rs12985258,rs143383,rs1480474,rs1558902,rs1707304,rs1887508,rs189934383,rs2075650,rs2247341,rs2716214,rs28514678,rs2902345,rs374892365,rs4606747,rs4759409,rs6066105,rs62070648,rs6945340,rs7091815,rs7174015,rs7240629,rs727479,rs7279363,rs7977132,rs9274666
Finngen Rheumatological endpoints	Liver iron content	Rheuma endpoints	Liver	MR Egger	38	-0.10	0.10	2.83E-01	0.91	rs1049213,rs10846653,rs10859587,rs114799031,rs116666910,rs12533942,rs13217173,rs144112342,rs147392974,rs1530588,rs1634727,rs1707334,rs2039028,rs206763,rs2071541,rs2075650,rs224333,rs2476601,rs2524075,rs2716214,rs2824183,rs3117072,rs3819406,rs4713669,rs4731532,rs511027,rs559411160,rs66989638,rs6927689,rs6929134,rs6934244,rs7563362,rs7578575,rs7731626,rs794367,rs9380146,rs9828491,rs9907843
Finngen Rheumatological endpoints	Liver iron content	Rheuma endpoints	Liver	Inverse variance weighted (fixed effects)	38	-0.11	0.02	9.22E-07	0.91	rs1049213,rs10846653,rs10859587,rs114799031,rs116666910,rs12533942,rs13217173,rs144112342,rs147392974,rs1530588,rs1634727,rs1707334,rs2039028,rs206763,rs2071541,rs2075650,rs224333,rs2476601,rs2524075,rs2716214,rs2824183,rs3117072,rs3819406,rs4713669,rs4731532,rs511027,rs559411160,rs66989638,rs6927689,rs6929134,rs6934244,rs7563362,rs7578575,rs7731626,rs794367,rs9380146,rs9828491,rs9907843
Finngen Rheumatological endpoints	Liver iron content	Rheuma endpoints	Liver	Inverse variance weighted (multiplicative random effects)	38	-0.11	0.05	3.00E-02	0.91	rs1049213,rs10846653,rs10859587,rs114799031,rs116666910,rs12533942,rs13217173,rs144112342,rs147392974,rs1530588,rs1634727,rs1707334,rs2039028,rs206763,rs2071541,rs2075650,rs224333,rs2476601,rs2524075,rs2716214,rs2824183,rs3117072,rs3819406,rs4713669,rs4731532,rs511027,rs559411160,rs66989638,rs6927689,rs6929134,rs6934244,rs7563362,rs7578575,rs7731626,rs794367,rs9380146,rs9828491,rs9907843
Finngen Rheumatological endpoints	Liver iron content	Rheuma endpoints	Liver	Weighted mode	38	-0.12	0.05	1.27E-02	0.91	rs1049213,rs10846653,rs10859587,rs114799031,rs116666910,rs12533942,rs13217173,rs144112342,rs147392974,rs1530588,rs1634727,rs1707334,rs2039028,rs206763,rs2071541,rs2075650,rs224333,rs2476601,rs2524075,rs2716214,rs2824183,rs3117072,rs3819406,rs4713669,rs4731532,rs511027,rs559411160,rs66989638,rs6927689,rs6929134,rs6934244,rs7563362,rs7578575,rs7731626,rs794367,rs9380146,rs9828491,rs9907843
Finngen Rheumatological endpoints	Liver iron content	Rheuma endpoints	Liver	Weighted median	38	-0.12	0.04	4.90E-03	0.91	rs1049213,rs10846653,rs10859587,rs114799031,rs116666910,rs12533942,rs13217173,rs144112342,rs147392974,rs1530588,rs1634727,rs1707334,rs2039028,rs206763,rs2071541,rs2075650,rs224333,rs2476601,rs2524075,rs2716214,rs2824183,rs3117072,rs3819406,rs4713669,rs4731532,rs511027,rs559411160,rs66989638,rs6927689,rs6929134,rs6934244,rs7563362,rs7578575,rs7731626,rs794367,rs9380146,rs9828491,rs9907843
Finngen Rheumatological endpoints	Liver iron content	Rheuma endpoints	Liver	DIVW	38	-0.11	0.02	5.45E-07	0.91	rs1049213,rs10846653,rs10859587,rs114799031,rs116666910,rs12533942,rs13217173,rs144112342,rs147392974,rs1530588,rs1634727,rs1707334,rs2039028,rs206763,rs2071541,rs2075650,rs224333,rs2476601,rs2524075,rs2716214,rs2824183,rs3117072,rs3819406,rs4713669,rs4731532,rs511027,rs559411160,rs66989638,rs6927689,rs6929134,rs6934244,rs7563362,rs7578575,rs7731626,rs794367,rs9380146,rs9828491,rs9907843
Finngen Rheumatological endpoints	Liver iron content	Rheuma endpoints	Liver	GRAPPLE	38	-0.11	0.04	1.30E-02	0.91	rs1049213,rs10846653,rs10859587,rs114799031,rs116666910,rs12533942,rs13217173,rs144112342,rs147392974,rs1530588,rs1634727,rs1707334,rs2039028,rs206763,rs2071541,rs2075650,rs224333,rs2476601,rs2524075,rs2716214,rs2824183,rs3117072,rs3819406,rs4713669,rs4731532,rs511027,rs559411160,rs66989638,rs6927689,rs6929134,rs6934244,rs7563362,rs7578575,rs7731626,rs794367,rs9380146,rs9828491,rs9907843
Finngen Rheumatological endpoints	Liver iron content	Rheuma endpoints	Liver	mr_raps	38	-0.11	0.02	3.02E-06	0.91	rs1049213,rs10846653,rs10859587,rs114799031,rs116666910,rs12533942,rs13217173,rs144112342,rs147392974,rs1530588,rs1634727,rs1707334,rs2039028,rs206763,rs2071541,rs2075650,rs224333,rs2476601,rs2524075,rs2716214,rs2824183,rs3117072,rs3819406,rs4713669,rs4731532,rs511027,rs559411160,rs66989638,rs6927689,rs6929134,rs6934244,rs7563362,rs7578575,rs7731626,rs794367,rs9380146,rs9828491,rs9907843
Statin medication	Liver iron content	IX Diseases of the circulatory system (I9_)	Liver	MR Egger	208	-0.03	0.02	6.91E-02	0.74	rs10107182,rs10283206,rs1035816,rs10402752,rs10420195,rs10455872,rs10495907,rs10518120,rs10789001,rs1081105,rs10882101,rs10888974,rs10891999,rs10897272,rs11134475,rs111737410,rs111839598,rs112108223,rs112298657,rs11242112,rs112647335,rs112675325,rs113414093,rs113674491,rs114165349,rs115415310,rs11571836,rs11589310,rs11591147,rs11601507,rs116843064,rs117733303,rs11880637,rs12047069,rs12128633,rs12149545,rs12154632,rs122283,rs1236717,rs1247359,rs12549603,rs12597024,rs1260326,rs12892542,rs12916,rs12952581,rs12974563,rs1305521,rs13389219,rs1367117,rs138270540,rs1391373,rs141657977,rs142224229,rs143020481,rs146765950,rs147223423,rs148046497,rs150380236,rs150382209,rs1516403,rs1535,rs1564348,rs162185,rs1660964,rs16848079,rs17111652,rs17111770,rs17120099,rs17243822,rs17393916,rs17424122,rs17528296,rs17642802,rs17689531,rs17699030,rs1800588,rs182611493,rs186965960,rs187779008,rs1883711,rs1962352,rs2073588,rs2107621,rs2112835,rs2126263,rs2129944,rs213498,rs217181,rs219562,rs2199048,rs2237897,rs2244608,rs2268569,rs2337382,rs2376866,rs2392929,rs2495503,rs2618566,rs2682544,rs2699429,rs2740488,rs28533705,rs28752924,rs28834106,rs28969414,rs2927437,rs2972144,rs3005923,rs311451,rs312052,rs3132469,rs326,rs333143,rs34931250,rs35165288,rs35656079,rs3734181,rs3737989,rs3775775,rs3918226,rs406315,rs41279633,rs41297875,rs41307428,rs41542613,rs4369782,rs4547448,rs4600084,rs4645936,rs4724229,rs4804149,rs4809404,rs4846922,rs4912425,rs4921915,rs4926690,rs496800,rs532315709,rs55714927,rs55809639,rs55871458,rs56028521,rs56261297,rs5746255,rs59509802,rs6016299,rs6028891,rs6102522,rs61824216,rs62118211,rs62120565,rs62459153,rs62482493,rs629301,rs635634,rs6459450,rs646356,rs6511720,rs6569648,rs6659406,rs6757883,rs6820938,rs687914,rs6905288,rs693668,rs7126310,rs71565765,rs7251161,rs7252391,rs72651833,rs72831817,rs73054338,rs73153978,rs73632723,rs738409,rs7412,rs7439202,rs75311177,rs75331444,rs75453571,rs7573769,rs75745507,rs7586471,rs7590687,rs76895963,rs769449,rs77442683,rs77645768,rs77653002,rs77691638,rs78333947,rs78470967,rs79010946,rs7903146,rs79834971,rs803073,rs807264,rs8103923,rs8107107,rs8113128,rs914830,rs9348441,rs9402686,rs964184,rs972283,rs9811074,rs9923147
Statin medication	Liver iron content	IX Diseases of the circulatory system (I9_)	Liver	Inverse variance weighted (fixed effects)	208	-0.04	0.01	4.01E-05	0.74	rs10107182,rs10283206,rs1035816,rs10402752,rs10420195,rs10455872,rs10495907,rs10518120,rs10789001,rs1081105,rs10882101,rs10888974,rs10891999,rs10897272,rs11134475,rs111737410,rs111839598,rs112108223,rs112298657,rs11242112,rs112647335,rs112675325,rs113414093,rs113674491,rs114165349,rs115415310,rs11571836,rs11589310,rs11591147,rs11601507,rs116843064,rs117733303,rs11880637,rs12047069,rs12128633,rs12149545,rs12154632,rs122283,rs1236717,rs1247359,rs12549603,rs12597024,rs1260326,rs12892542,rs12916,rs12952581,rs12974563,rs1305521,rs13389219,rs1367117,rs138270540,rs1391373,rs141657977,rs142224229,rs143020481,rs146765950,rs147223423,rs148046497,rs150380236,rs150382209,rs1516403,rs1535,rs1564348,rs162185,rs1660964,rs16848079,rs17111652,rs17111770,rs17120099,rs17243822,rs17393916,rs17424122,rs17528296,rs17642802,rs17689531,rs17699030,rs1800588,rs182611493,rs186965960,rs187779008,rs1883711,rs1962352,rs2073588,rs2107621,rs2112835,rs2126263,rs2129944,rs213498,rs217181,rs219562,rs2199048,rs2237897,rs2244608,rs2268569,rs2337382,rs2376866,rs2392929,rs2495503,rs2618566,rs2682544,rs2699429,rs2740488,rs28533705,rs28752924,rs28834106,rs28969414,rs2927437,rs2972144,rs3005923,rs311451,rs312052,rs3132469,rs326,rs333143,rs34931250,rs35165288,rs35656079,rs3734181,rs3737989,rs3775775,rs3918226,rs406315,rs41279633,rs41297875,rs41307428,rs41542613,rs4369782,rs4547448,rs4600084,rs4645936,rs4724229,rs4804149,rs4809404,rs4846922,rs4912425,rs4921915,rs4926690,rs496800,rs532315709,rs55714927,rs55809639,rs55871458,rs56028521,rs56261297,rs5746255,rs59509802,rs6016299,rs6028891,rs6102522,rs61824216,rs62118211,rs62120565,rs62459153,rs62482493,rs629301,rs635634,rs6459450,rs646356,rs6511720,rs6569648,rs6659406,rs6757883,rs6820938,rs687914,rs6905288,rs693668,rs7126310,rs71565765,rs7251161,rs7252391,rs72651833,rs72831817,rs73054338,rs73153978,rs73632723,rs738409,rs7412,rs7439202,rs75311177,rs75331444,rs75453571,rs7573769,rs75745507,rs7586471,rs7590687,rs76895963,rs769449,rs77442683,rs77645768,rs77653002,rs77691638,rs78333947,rs78470967,rs79010946,rs7903146,rs79834971,rs803073,rs807264,rs8103923,rs8107107,rs8113128,rs914830,rs9348441,rs9402686,rs964184,rs972283,rs9811074,rs9923147
Statin medication	Liver iron content	IX Diseases of the circulatory system (I9_)	Liver	Inverse variance weighted (multiplicative random effects)	208	-0.04	0.01	6.63E-04	0.74	rs10107182,rs10283206,rs1035816,rs10402752,rs10420195,rs10455872,rs10495907,rs10518120,rs10789001,rs1081105,rs10882101,rs10888974,rs10891999,rs10897272,rs11134475,rs111737410,rs111839598,rs112108223,rs112298657,rs11242112,rs112647335,rs112675325,rs113414093,rs113674491,rs114165349,rs115415310,rs11571836,rs11589310,rs11591147,rs11601507,rs116843064,rs117733303,rs11880637,rs12047069,rs12128633,rs12149545,rs12154632,rs122283,rs1236717,rs1247359,rs12549603,rs12597024,rs1260326,rs12892542,rs12916,rs12952581,rs12974563,rs1305521,rs13389219,rs1367117,rs138270540,rs1391373,rs141657977,rs142224229,rs143020481,rs146765950,rs147223423,rs148046497,rs150380236,rs150382209,rs1516403,rs1535,rs1564348,rs162185,rs1660964,rs16848079,rs17111652,rs17111770,rs17120099,rs17243822,rs17393916,rs17424122,rs17528296,rs17642802,rs17689531,rs17699030,rs1800588,rs182611493,rs186965960,rs187779008,rs1883711,rs1962352,rs2073588,rs2107621,rs2112835,rs2126263,rs2129944,rs213498,rs217181,rs219562,rs2199048,rs2237897,rs2244608,rs2268569,rs2337382,rs2376866,rs2392929,rs2495503,rs2618566,rs2682544,rs2699429,rs2740488,rs28533705,rs28752924,rs28834106,rs28969414,rs2927437,rs2972144,rs3005923,rs311451,rs312052,rs3132469,rs326,rs333143,rs34931250,rs35165288,rs35656079,rs3734181,rs3737989,rs3775775,rs3918226,rs406315,rs41279633,rs41297875,rs41307428,rs41542613,rs4369782,rs4547448,rs4600084,rs4645936,rs4724229,rs4804149,rs4809404,rs4846922,rs4912425,rs4921915,rs4926690,rs496800,rs532315709,rs55714927,rs55809639,rs55871458,rs56028521,rs56261297,rs5746255,rs59509802,rs6016299,rs6028891,rs6102522,rs61824216,rs62118211,rs62120565,rs62459153,rs62482493,rs629301,rs635634,rs6459450,rs646356,rs6511720,rs6569648,rs6659406,rs6757883,rs6820938,rs687914,rs6905288,rs693668,rs7126310,rs71565765,rs7251161,rs7252391,rs72651833,rs72831817,rs73054338,rs73153978,rs73632723,rs738409,rs7412,rs7439202,rs75311177,rs75331444,rs75453571,rs7573769,rs75745507,rs7586471,rs7590687,rs76895963,rs769449,rs77442683,rs77645768,rs77653002,rs77691638,rs78333947,rs78470967,rs79010946,rs7903146,rs79834971,rs803073,rs807264,rs8103923,rs8107107,rs8113128,rs914830,rs9348441,rs9402686,rs964184,rs972283,rs9811074,rs9923147
Statin medication	Liver iron content	IX Diseases of the circulatory system (I9_)	Liver	Weighted mode	208	-0.03	0.02	2.50E-02	0.74	rs10107182,rs10283206,rs1035816,rs10402752,rs10420195,rs10455872,rs10495907,rs10518120,rs10789001,rs1081105,rs10882101,rs10888974,rs10891999,rs10897272,rs11134475,rs111737410,rs111839598,rs112108223,rs112298657,rs11242112,rs112647335,rs112675325,rs113414093,rs113674491,rs114165349,rs115415310,rs11571836,rs11589310,rs11591147,rs11601507,rs116843064,rs117733303,rs11880637,rs12047069,rs12128633,rs12149545,rs12154632,rs122283,rs1236717,rs1247359,rs12549603,rs12597024,rs1260326,rs12892542,rs12916,rs12952581,rs12974563,rs1305521,rs13389219,rs1367117,rs138270540,rs1391373,rs141657977,rs142224229,rs143020481,rs146765950,rs147223423,rs148046497,rs150380236,rs150382209,rs1516403,rs1535,rs1564348,rs162185,rs1660964,rs16848079,rs17111652,rs17111770,rs17120099,rs17243822,rs17393916,rs17424122,rs17528296,rs17642802,rs17689531,rs17699030,rs1800588,rs182611493,rs186965960,rs187779008,rs1883711,rs1962352,rs2073588,rs2107621,rs2112835,rs2126263,rs2129944,rs213498,rs217181,rs219562,rs2199048,rs2237897,rs2244608,rs2268569,rs2337382,rs2376866,rs2392929,rs2495503,rs2618566,rs2682544,rs2699429,rs2740488,rs28533705,rs28752924,rs28834106,rs28969414,rs2927437,rs2972144,rs3005923,rs311451,rs312052,rs3132469,rs326,rs333143,rs34931250,rs35165288,rs35656079,rs3734181,rs3737989,rs3775775,rs3918226,rs406315,rs41279633,rs41297875,rs41307428,rs41542613,rs4369782,rs4547448,rs4600084,rs4645936,rs4724229,rs4804149,rs4809404,rs4846922,rs4912425,rs4921915,rs4926690,rs496800,rs532315709,rs55714927,rs55809639,rs55871458,rs56028521,rs56261297,rs5746255,rs59509802,rs6016299,rs6028891,rs6102522,rs61824216,rs62118211,rs62120565,rs62459153,rs62482493,rs629301,rs635634,rs6459450,rs646356,rs6511720,rs6569648,rs6659406,rs6757883,rs6820938,rs687914,rs6905288,rs693668,rs7126310,rs71565765,rs7251161,rs7252391,rs72651833,rs72831817,rs73054338,rs73153978,rs73632723,rs738409,rs7412,rs7439202,rs75311177,rs75331444,rs75453571,rs7573769,rs75745507,rs7586471,rs7590687,rs76895963,rs769449,rs77442683,rs77645768,rs77653002,rs77691638,rs78333947,rs78470967,rs79010946,rs7903146,rs79834971,rs803073,rs807264,rs8103923,rs8107107,rs8113128,rs914830,rs9348441,rs9402686,rs964184,rs972283,rs9811074,rs9923147
Statin medication	Liver iron content	IX Diseases of the circulatory system (I9_)	Liver	Weighted median	208	-0.04	0.02	9.80E-03	0.74	rs10107182,rs10283206,rs1035816,rs10402752,rs10420195,rs10455872,rs10495907,rs10518120,rs10789001,rs1081105,rs10882101,rs10888974,rs10891999,rs10897272,rs11134475,rs111737410,rs111839598,rs112108223,rs112298657,rs11242112,rs112647335,rs112675325,rs113414093,rs113674491,rs114165349,rs115415310,rs11571836,rs11589310,rs11591147,rs11601507,rs116843064,rs117733303,rs11880637,rs12047069,rs12128633,rs12149545,rs12154632,rs122283,rs1236717,rs1247359,rs12549603,rs12597024,rs1260326,rs12892542,rs12916,rs12952581,rs12974563,rs1305521,rs13389219,rs1367117,rs138270540,rs1391373,rs141657977,rs142224229,rs143020481,rs146765950,rs147223423,rs148046497,rs150380236,rs150382209,rs1516403,rs1535,rs1564348,rs162185,rs1660964,rs16848079,rs17111652,rs17111770,rs17120099,rs17243822,rs17393916,rs17424122,rs17528296,rs17642802,rs17689531,rs17699030,rs1800588,rs182611493,rs186965960,rs187779008,rs1883711,rs1962352,rs2073588,rs2107621,rs2112835,rs2126263,rs2129944,rs213498,rs217181,rs219562,rs2199048,rs2237897,rs2244608,rs2268569,rs2337382,rs2376866,rs2392929,rs2495503,rs2618566,rs2682544,rs2699429,rs2740488,rs28533705,rs28752924,rs28834106,rs28969414,rs2927437,rs2972144,rs3005923,rs311451,rs312052,rs3132469,rs326,rs333143,rs34931250,rs35165288,rs35656079,rs3734181,rs3737989,rs3775775,rs3918226,rs406315,rs41279633,rs41297875,rs41307428,rs41542613,rs4369782,rs4547448,rs4600084,rs4645936,rs4724229,rs4804149,rs4809404,rs4846922,rs4912425,rs4921915,rs4926690,rs496800,rs532315709,rs55714927,rs55809639,rs55871458,rs56028521,rs56261297,rs5746255,rs59509802,rs6016299,rs6028891,rs6102522,rs61824216,rs62118211,rs62120565,rs62459153,rs62482493,rs629301,rs635634,rs6459450,rs646356,rs6511720,rs6569648,rs6659406,rs6757883,rs6820938,rs687914,rs6905288,rs693668,rs7126310,rs71565765,rs7251161,rs7252391,rs72651833,rs72831817,rs73054338,rs73153978,rs73632723,rs738409,rs7412,rs7439202,rs75311177,rs75331444,rs75453571,rs7573769,rs75745507,rs7586471,rs7590687,rs76895963,rs769449,rs77442683,rs77645768,rs77653002,rs77691638,rs78333947,rs78470967,rs79010946,rs7903146,rs79834971,rs803073,rs807264,rs8103923,rs8107107,rs8113128,rs914830,rs9348441,rs9402686,rs964184,rs972283,rs9811074,rs9923147
Statin medication	Liver iron content	IX Diseases of the circulatory system (I9_)	Liver	DIVW	208	-0.04	0.01	2.02E-05	0.74	rs10107182,rs10283206,rs1035816,rs10402752,rs10420195,rs10455872,rs10495907,rs10518120,rs10789001,rs1081105,rs10882101,rs10888974,rs10891999,rs10897272,rs11134475,rs111737410,rs111839598,rs112108223,rs112298657,rs11242112,rs112647335,rs112675325,rs113414093,rs113674491,rs114165349,rs115415310,rs11571836,rs11589310,rs11591147,rs11601507,rs116843064,rs117733303,rs11880637,rs12047069,rs12128633,rs12149545,rs12154632,rs122283,rs1236717,rs1247359,rs12549603,rs12597024,rs1260326,rs12892542,rs12916,rs12952581,rs12974563,rs1305521,rs13389219,rs1367117,rs138270540,rs1391373,rs141657977,rs142224229,rs143020481,rs146765950,rs147223423,rs148046497,rs150380236,rs150382209,rs1516403,rs1535,rs1564348,rs162185,rs1660964,rs16848079,rs17111652,rs17111770,rs17120099,rs17243822,rs17393916,rs17424122,rs17528296,rs17642802,rs17689531,rs17699030,rs1800588,rs182611493,rs186965960,rs187779008,rs1883711,rs1962352,rs2073588,rs2107621,rs2112835,rs2126263,rs2129944,rs213498,rs217181,rs219562,rs2199048,rs2237897,rs2244608,rs2268569,rs2337382,rs2376866,rs2392929,rs2495503,rs2618566,rs2682544,rs2699429,rs2740488,rs28533705,rs28752924,rs28834106,rs28969414,rs2927437,rs2972144,rs3005923,rs311451,rs312052,rs3132469,rs326,rs333143,rs34931250,rs35165288,rs35656079,rs3734181,rs3737989,rs3775775,rs3918226,rs406315,rs41279633,rs41297875,rs41307428,rs41542613,rs4369782,rs4547448,rs4600084,rs4645936,rs4724229,rs4804149,rs4809404,rs4846922,rs4912425,rs4921915,rs4926690,rs496800,rs532315709,rs55714927,rs55809639,rs55871458,rs56028521,rs56261297,rs5746255,rs59509802,rs6016299,rs6028891,rs6102522,rs61824216,rs62118211,rs62120565,rs62459153,rs62482493,rs629301,rs635634,rs6459450,rs646356,rs6511720,rs6569648,rs6659406,rs6757883,rs6820938,rs687914,rs6905288,rs693668,rs7126310,rs71565765,rs7251161,rs7252391,rs72651833,rs72831817,rs73054338,rs73153978,rs73632723,rs738409,rs7412,rs7439202,rs75311177,rs75331444,rs75453571,rs7573769,rs75745507,rs7586471,rs7590687,rs76895963,rs769449,rs77442683,rs77645768,rs77653002,rs77691638,rs78333947,rs78470967,rs79010946,rs7903146,rs79834971,rs803073,rs807264,rs8103923,rs8107107,rs8113128,rs914830,rs9348441,rs9402686,rs964184,rs972283,rs9811074,rs9923147
Statin medication	Liver iron content	IX Diseases of the circulatory system (I9_)	Liver	GRAPPLE	208	-0.03	0.01	4.34E-03	0.74	rs10107182,rs10283206,rs1035816,rs10402752,rs10420195,rs10455872,rs10495907,rs10518120,rs10789001,rs1081105,rs10882101,rs10888974,rs10891999,rs10897272,rs11134475,rs111737410,rs111839598,rs112108223,rs112298657,rs11242112,rs112647335,rs112675325,rs113414093,rs113674491,rs114165349,rs115415310,rs11571836,rs11589310,rs11591147,rs11601507,rs116843064,rs117733303,rs11880637,rs12047069,rs12128633,rs12149545,rs12154632,rs122283,rs1236717,rs1247359,rs12549603,rs12597024,rs1260326,rs12892542,rs12916,rs12952581,rs12974563,rs1305521,rs13389219,rs1367117,rs138270540,rs1391373,rs141657977,rs142224229,rs143020481,rs146765950,rs147223423,rs148046497,rs150380236,rs150382209,rs1516403,rs1535,rs1564348,rs162185,rs1660964,rs16848079,rs17111652,rs17111770,rs17120099,rs17243822,rs17393916,rs17424122,rs17528296,rs17642802,rs17689531,rs17699030,rs1800588,rs182611493,rs186965960,rs187779008,rs1883711,rs1962352,rs2073588,rs2107621,rs2112835,rs2126263,rs2129944,rs213498,rs217181,rs219562,rs2199048,rs2237897,rs2244608,rs2268569,rs2337382,rs2376866,rs2392929,rs2495503,rs2618566,rs2682544,rs2699429,rs2740488,rs28533705,rs28752924,rs28834106,rs28969414,rs2927437,rs2972144,rs3005923,rs311451,rs312052,rs3132469,rs326,rs333143,rs34931250,rs35165288,rs35656079,rs3734181,rs3737989,rs3775775,rs3918226,rs406315,rs41279633,rs41297875,rs41307428,rs41542613,rs4369782,rs4547448,rs4600084,rs4645936,rs4724229,rs4804149,rs4809404,rs4846922,rs4912425,rs4921915,rs4926690,rs496800,rs532315709,rs55714927,rs55809639,rs55871458,rs56028521,rs56261297,rs5746255,rs59509802,rs6016299,rs6028891,rs6102522,rs61824216,rs62118211,rs62120565,rs62459153,rs62482493,rs629301,rs635634,rs6459450,rs646356,rs6511720,rs6569648,rs6659406,rs6757883,rs6820938,rs687914,rs6905288,rs693668,rs7126310,rs71565765,rs7251161,rs7252391,rs72651833,rs72831817,rs73054338,rs73153978,rs73632723,rs738409,rs7412,rs7439202,rs75311177,rs75331444,rs75453571,rs7573769,rs75745507,rs7586471,rs7590687,rs76895963,rs769449,rs77442683,rs77645768,rs77653002,rs77691638,rs78333947,rs78470967,rs79010946,rs7903146,rs79834971,rs803073,rs807264,rs8103923,rs8107107,rs8113128,rs914830,rs9348441,rs9402686,rs964184,rs972283,rs9811074,rs9923147
Statin medication	Liver iron content	IX Diseases of the circulatory system (I9_)	Liver	mr_raps	208	-0.03	0.01	7.48E-04	0.74	rs10107182,rs10283206,rs1035816,rs10402752,rs10420195,rs10455872,rs10495907,rs10518120,rs10789001,rs1081105,rs10882101,rs10888974,rs10891999,rs10897272,rs11134475,rs111737410,rs111839598,rs112108223,rs112298657,rs11242112,rs112647335,rs112675325,rs113414093,rs113674491,rs114165349,rs115415310,rs11571836,rs11589310,rs11591147,rs11601507,rs116843064,rs117733303,rs11880637,rs12047069,rs12128633,rs12149545,rs12154632,rs122283,rs1236717,rs1247359,rs12549603,rs12597024,rs1260326,rs12892542,rs12916,rs12952581,rs12974563,rs1305521,rs13389219,rs1367117,rs138270540,rs1391373,rs141657977,rs142224229,rs143020481,rs146765950,rs147223423,rs148046497,rs150380236,rs150382209,rs1516403,rs1535,rs1564348,rs162185,rs1660964,rs16848079,rs17111652,rs17111770,rs17120099,rs17243822,rs17393916,rs17424122,rs17528296,rs17642802,rs17689531,rs17699030,rs1800588,rs182611493,rs186965960,rs187779008,rs1883711,rs1962352,rs2073588,rs2107621,rs2112835,rs2126263,rs2129944,rs213498,rs217181,rs219562,rs2199048,rs2237897,rs2244608,rs2268569,rs2337382,rs2376866,rs2392929,rs2495503,rs2618566,rs2682544,rs2699429,rs2740488,rs28533705,rs28752924,rs28834106,rs28969414,rs2927437,rs2972144,rs3005923,rs311451,rs312052,rs3132469,rs326,rs333143,rs34931250,rs35165288,rs35656079,rs3734181,rs3737989,rs3775775,rs3918226,rs406315,rs41279633,rs41297875,rs41307428,rs41542613,rs4369782,rs4547448,rs4600084,rs4645936,rs4724229,rs4804149,rs4809404,rs4846922,rs4912425,rs4921915,rs4926690,rs496800,rs532315709,rs55714927,rs55809639,rs55871458,rs56028521,rs56261297,rs5746255,rs59509802,rs6016299,rs6028891,rs6102522,rs61824216,rs62118211,rs62120565,rs62459153,rs62482493,rs629301,rs635634,rs6459450,rs646356,rs6511720,rs6569648,rs6659406,rs6757883,rs6820938,rs687914,rs6905288,rs693668,rs7126310,rs71565765,rs7251161,rs7252391,rs72651833,rs72831817,rs73054338,rs73153978,rs73632723,rs738409,rs7412,rs7439202,rs75311177,rs75331444,rs75453571,rs7573769,rs75745507,rs7586471,rs7590687,rs76895963,rs769449,rs77442683,rs77645768,rs77653002,rs77691638,rs78333947,rs78470967,rs79010946,rs7903146,rs79834971,rs803073,rs807264,rs8103923,rs8107107,rs8113128,rs914830,rs9348441,rs9402686,rs964184,rs972283,rs9811074,rs9923147

Abdomen & clinical endpoints

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Overview of Abdomen MR results

Clinical endpoints -> Abdomen

Abdomen -> Clinical endpoints

Abdominal MR results

Abdomen to clinical outcomes

Clinical outcomes to abdomen