Welcome to MR Atlas!
This website presents primary findings of phenotypic and genetic connections between multiple organ imaging traits and clinical outcomes. Please see the paper for a full description of results and methods (https://www.medrxiv.org/content/10.1101/2023.05.22.23290355v1).
Imaging Traits
Brain MRI
301 Brain MRI traits contains 3 modalities : network level functional MRI, DTI parameters and region brain volume (T1).
Heart CMR
82 Heart CMR traits contains imaging data from 6 sectors, namely AAo, DAo, LV, RV, LA and LA.
Abdominal MRI
11 Abdominal MRI traits cover different organs or tissues, such as lung, liver, pancreas, spleen and adipose.
Skeleton DXA
8 Skeleton DXA traits measure length or width of several skeletons, such as shoulder, tibia, torso, hip and forearm.
Finngen Clinical Endpoints
88 FinnGen traits were selected from FinnGen database, including 11 categories, such as cardiometabolic endpoints, diseases of circulatory system and mental and behavioural disorders.
Results
Brain-diseases connnection
Results from Mendelian randomization, LDSC, LAVA, PRS after Bonferroni adjustment.
Heart-diseases
connection
Results from Mendelian randomization, LDSC, LAVA, PRS after Bonferroni adjustment.
Abdomen-diseases connection
Results from Mendelian randomization after Bonferroni adjustment.
Skeleton-diseases
connection
Results from Mendelian randomization after Bonferroni adjustment.
